adenylate cyclase

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adenylate cyclase

 [ah-den´ĭ-lāt si´clās]
an enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic adenosine monophosphate (cAMP) and inorganic pyrophosphate (PPi ). It is activated by the attachment of a hormone or neurotransmitter to a specific membrane-bound receptor.

a·den·y·late cy·clase

an enzyme acting on ATP to form 3',5'-cyclic AMP plus pyrophosphate, a crucial step in the regulation and formation of second messengers.
Synonym(s): 3', 5'-cyclic AMP synthetase

adenylate cyclase

(ə-dĕn′əl-ĭt, ăd′n-ĭl′ĭt) also

adenyl cyclase

(ə-dĕn′əl, ăd′n-ĭl)
n.
An enzyme that catalyzes the formation of cyclic AMP from ATP and plays a key role in signal transduction.

adenylate cyclase

an enzyme that initiates the conversion of adenosine triphosphate to cyclic adenosine monophosphate, a mediator of many physiological activities.

Adenylate Cyclase

An enzyme that catalyses ATP to form 3’,5’-cyclic AMP and inorganic pyrophosphate. G proteins dissociate into GTP-bound alpha subunits—activating adenylyl cyclase, retinal phosphodiesterase, phospholipase C, and ion channels—and a complex of beta and gamma subunits, selectively activating certain forms of adenylate cyclase following interaction with the cell receptors. Adenylate cyclase is intimately linked to the receptor-G protein machinery on the cytoplasmic face of cell membrane, which generates the second messenger, cAMP, when stimulated by an extracellular message in the form of receptor binding of a hormone or other ligand, light, or odours. Adenylate cyclase is the prototypic second messenger generator, and is regulated by one or the other arm of the phospholipase C pathway. It is further regulated by cyclic changes in cAMP and internal Ca2+ levels.

a·den·y·late cy·clase

(ă-den'i-lāt sī'klās)
An enzyme acting on ATP to form 3',5'-cyclic AMP plus pyrophosphate. A crucial step in the regulation and formation of second messengers.
Synonym(s): 3', 5'-cyclic AMP synthetase.

adenylate cyclase

The enzyme that converts ADENOSINE TRIPHOSPHATE (ATP) to cyclic AMP.

adenylate

a salt, anion or ester of adenylic acid.

adenylate cyclase
an enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic adenosine monophosphate (cAMP) and inorganic pyrophosphate. It is activated by the attachment of a hormone or neurotransmitter to a specific membrane-bound receptor.
adenylate kinase
enzyme catalyzing the conversion of two moles of ADP to ATP and AMP, thereby equilibrating ADP with ATP and AMP. Controls the adenylate energy charge of a cell, particularly muscle cells. Called also myokinase.