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EAE |
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EAE 1. experimental allergic encephalomyelitis. 2. enzootic abortion of ewes. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| Stephen Miller, PhD, and his team at Northwestern University Feinberg School of Medicine in Chicago, have shown that mice with an MS-like disease called EAE have fewer relapses when they are treated with a mixture of small bits of myelin proteins and signal cells programmed to suspend T cell activation. Hooper and his colleagues had reported earlier that they could prevent most EAE symptoms by giving mice uric acid before inducing the disease. In mice that were genetically engineered to lack the osteopontin gene, the progression of EAE was inhibited, and the severity of the disease significantly reduced. |
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