sorbitol

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sorbitol

 [sor´bĭ-tol]
a six-carbon sugar alcohol from a variety of fruits, found in lens deposits in diabetes mellitus. A pharmaceutical preparation is used as a sweetening agent and osmotic laxative, and in drugs as a tablet excipient, moistening agent, and stabilizer.

sor·bi·tol

(sōr'bi-tol),
A reduction product of glucose and sorbose found in the berries of the rowan/mountain ash, Sorbus aucuparia (family Rosaceae), and in many fruits and seaweeds. It has many industrial and pharmaceutical uses; medicinally, it is used as a laxative and as a sweetening agent, and is almost completely metabolized (to CO2 and H2O); accumulates in Type 1 diabetes mellitus; elevated levels can cause osmotic damage.
Synonym(s): sorbite

sorbitol

/sor·bi·tol/ (sor´bĭ-tol) a six-carbon sugar alcohol from a variety of fruits, found in lens deposits in diabetes mellitus. A pharmaceutical preparation is used as a sweetening agent and osmotic laxative, and in drugs as a tablet excipient, humectant, and stabilizer.

sorbitol

(sôr′bĭ-tôl′, -tōl′, -tŏl′)
n.
A white, sweetish, crystalline alcohol, C6H8(OH)6, found in various berries and fruits or prepared synthetically and used as a flavoring agent, a sugar substitute for people with diabetes, and a moisturizer in cosmetics and other products.

sorbitol

A polyhydroxyl alcohol or polyol synthesized from glucose by aldose reductase in neural tissue, produced in excess in DM; sorbitol may be further metabolized to fructose, which together cause ↑ osmotic pressure, intracellular edema, Schwann cell swelling, anoxia and nerve demyelination; it has been implicated in diabetic neuropathy; it has been used as an artificial sweetener. Cf Advanced glycosylation endproducts.

sor·bi·tol

(sōr'bi-tol)
Reduction product in many fruits and seaweeds that has many industrial and pharmaceutical uses; used as a laxative and as a sweetening agent.

sorbitol

A sweetening agent derived from glucose.

sor·bi·tol

(sōr'bi-tol)
Reduction product of glucose and sorbose found in the berries of rowan/mountain ash, Sorbus aucuparia, and in many other fruits and seaweeds. Has many industrial and pharmaceutical uses.

sorbitol

a sugar alcohol found in various berries and fruits; in mammals, sorbitol is an intermediate in the conversion of glucose to fructose. It is found in lens deposits in diabetes mellitus. A 50% solution is used as an osmotic diuretic. Sorbitol is used as a sweetener in some dietetic foods; it has the same caloric value as other sugars.

sorbitol dehydrogenase
called also SDH; see l-iditol dehydrogenase (ID).
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