RNF6

(redirected from E3 ubiquitin-protein ligase RNF6)

RNF6

A gene on chromosome 13q12.2 that encodes an E3 ubiquitin-protein ligase and a putative tumour suppressor, which has a RING finger motif.

Molecular pathology
RNF6 mutations are well-described in squamous cell carcinoma of the oesophagus.