E2F6

E2F6

A gene on chromosome 2p25.1 that encodes a member of the E2F family of DNA-binding transcription factors, which play a key role in regulating the cell cycle and tumour suppressor proteins. E2F6 lacks transactivation and tumour suppressor protein association domains; it has a modular suppression domain and inhibits E2F-dependent transcription.
References in periodicals archive ?
Phosphatidic acid phosphatase type 2A (PPAP2A), E2F6, and S1Pr2 genes were related to the enriched pathway.
In the small intestine, all genes (BRMS1, DSP, E2F6, NUMA1, and PPAP2A) except S1PR2 were directly connected with ubiquitin C to form a network concerned with cancer, cell to cell signaling and interaction and cellular growth and proliferation.
Also, the Bcl-w and E2F6 stable expressing WPE-1 NA22 cell lines showed high resistance to various chemotherapeutic drugs.
46 7SK RNA [Source:RFAM;Acc:RF00100] ENSSSCG00000012939 BRMS1 breast cancer metastasis suppressor 1 [Source:HGNC Symbol;Acc:17262] ENSSSCG00000013658 S1PR2 sphingosine-1-phosphate receptor 2 [Source:HGNC Symbol;Acc:3169] ENSSSCG00000026161 E2F6 E2F transcription factor 6 [Source:HGNC Symbol;Acc:3120] ENSSSCG00000001025 DSP desmoplakin [Source:HGNC Symbol;Acc:3052] ENSSSCG00000014802 NUMA1 nuclear mitotic apparatus protein 1 [Source:HGNC Symbol;Acc:8059] ENSSSCG00000016912 PPAP2A phosphatidic acid phosphatase type 2A [Source:HGNC Symbol;Acc:9228] ENSSSCG00000030936 CH242-154K8.
56E-05 Plumage part rs ID Gene Location Head rs14398623 RNF144A Intron rs318020030 PPP1R9B Intron rs16669242 FGF12 Intergenic GGaluGA105119 ENSGALG000 Intergenic 00023628 rs14112979 HELZ Intron Wing rs13982792 XPO4 Intron rs14131527 XIRP1 Intron rs14188826 PRL Intergenic rs14339964 AKT3 Intron rs14404313 NT5C1B Intergenic GGaluGA110134 MSI1 Intron rs15027075 PBX3 Intron Breast rs14316836 LCLAT1 Intron Back rs14401050 E2F6 Intergenic rs15616451 ENSGALG000 Intergenic 00020136 GGaluGA287070 VRK1 Intergenic GGaluGA095084 SGCD Intron rs15022353 TTC28 Intron (1) Minor allele/Major allele.