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dynorphin

   Also found in: Wikipedia 0.02 sec.
dynorphin /dy·nor·phin/ (di-nor´fin) any of a family of opioid peptides found throughout the central and peripheral nervous systems; most are agonists at opioid receptor sites. Some are probably involved in pain regulation and others in the hypothalamic regulation of eating and drinking.
dynorphin
[dīnôr′fən]
an endogenous opioid derived from the prohormone prodynorphin. It is a neuroactive peptide with potent analgesic effects.


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Effect of low- and high-frequency TENS on Met-enkephalin-Arg-Phe and dynorphin A immunoreactivity in human lumbar CSF.
In contrast to the new work, some experiments have shown that dynorphin actually promotes pain.
Dynorphin A is being developed as an analgesic agent, initially as an adjunct to opioid therapy.
 
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