Duane syndrome(redirected from Dwayne's syndrome)
a retraction of the globe and pseudoptosis on attempted adduction; due to coinnervation of the horizontal recti. Sometimes there is an inability to abduct the affected eye (type 1), or adduct the affected eye (type 2), or both (type 3).
Synonym(s): Duane syndrome
Duane radial ray syndromeAn autosomal dominant condition (MIM:102490) characterised by limited external rotation of the eyes and retraction with inward rotation, and by radial-ray-type bone defects in the hands (e.g., malformed or absent thumbs, extra thumb or finger-like thumb) and forearms (e.g., absence of one or more forearm bones); it may be accompanied by renal defects.
DRRS is caused by mutations of SALL4, which encodes a zinc finger transcription factor thought to play a role in musculoskeletal embryogenesis.
[Alexander Duane, U.S. ophthalmologist, 1858–1926]
A disorder of eye movement in which the affected eye does not move centrally or temporally in a normal manner and pulls into the orbit on adduction.
Duane,Alexander, U.S. ophthalmologist, 1858-1926.
Duane syndrome - a retraction of the globe and pseudoptosis on attempted adduction. Synonym(s): retraction syndrome