lymphogranuloma /lym·pho·gran·u·lo·ma/ (-gran″u-lo´mah) Hodgkin's disease.
lymphogranuloma [lim″fo-gran″u-lo´mah]
lymphogranuloma inguina´le , lymphogranuloma vene´reum a venereal infection due to strains of Chlamydia trachomatis, marked by a primary transient ulcerative lesion of the genitals, followed by acute lymphadenopathy. In men, primary infection on the penis usually leads to inguinal lymphadenitis; in women, primary infection of the labia, vagina, or cervix often leads to hemorrhagic proctocolitis, and may progress to ulcerations, rectal strictures, rectovaginal fistulas, and genital elephantiasis.
lym·pho·gran·u·lo·ma (l m f -gr ny -l m)n. 1. Any of several unrelated diseases in which the pathological processes result in the formation of granulomas or granulomalike lesions, especially in various groups of lymph nodes which then become conspicuously enlarged. 2. Hodgkin's disease. No longer in technical use. |
lymphogranuloma [lim″fo-gran″u-lo´mah]
lymphogranuloma inguina´le (venereal lymphogranuloma) (lymphogranuloma vene´reum) a sexually transmitted disease caused by a strain of Chlamydia trachomatis, which affects the lymph organs in the genital area. It occurs most frequently in tropical and semitropical regions. Three to 21 days after the body is infected, a small, hard sore appears in the genital area. The disease soon spreads from the local sore to the lymph nodes, particularly those in the groin; nodes may swell to the size of a walnut. Since they seldom break open and drain pus, the swellings may remain for months unless aspirated. In women with the disease, the vulva may become greatly enlarged. The rectum may become narrowed, so that surgery is necessary for relief. In the early stages of the disease, there may also be inflammation of the joints, skin rashes, and fever. Sometimes the brain and meninges are affected. It is thought that after the initial sore heals, men may no longer transmit the disease. Women, however, may infect sexual partners for years. The condition may be successfully treated with doxycycline or erythromycin.
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