Dulcolax


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Related to Dulcolax: Dulcolax Stool Softener

bisacodyl

Alophen, Apo-bisacodyl (CA), Biolax (UK), Bisac-Evac, Biscolax, Carter's Little Pills (CA), Correctol, Dacodyl, Doxidan, Dulcolax, Ex-Lax Ultra, Femilax, Fleet Bisacodyl, Fleet Stimulant Laxative, Gentlax (CA), Laxoberal (UK), Veracolate

Pharmacologic class: Stimulant laxative

Therapeutic class: Laxative

Pregnancy risk category B

Action

Unclear. Thought to stimulate colonic mucosa, producing parasympathetic reflexes that enhance peristalsis and increase water and electrolyte secretion, thereby causing evacuation of colon.

Availability

Enema: 0.33 mg/ml, 10 mg/ml

Powder for rectal solution: 1.5 mg bisacodyl and 2.5 g tannic acid

Suppositories (rectal): 5 mg, 10 mg

Tablets (enteric-coated): 5 mg

Indications and dosages

Constipation; bowel cleansing for childbirth, surgery, and endoscopic examination

Adults and children ages 12 and older: 5 to 15 mg P.O. or 10 mg P.R. as a single dose

Children older than age 3: 5 to 10 mg or 0.3 mg/kg P.O. as a single dose

Children ages 2 and older: 5 to 10 mg P.R. as a single dose

Children younger than age 2: 5 mg P.R. as a single dose

Contraindications

• Hypersensitivity to drug
• Intestinal obstruction
• Gastroenteritis
• Appendicitis

Precautions

Use cautiously in:
• hypersensitivity to tannic acid
• severe cardiovascular disease, anal or rectal fissures
• pregnant or breastfeeding patients.

Administration

• Make sure patient swallows tablets whole without chewing.
• Don't give tablets within 1 hour of dairy products or antacids (may break down enteric coating).
• Know that drug should be used only for short periods.

Adverse reactions

CNS: dizziness, syncope

GI: nausea, vomiting, diarrhea (with high doses), abdominal pain, burning sensation in rectum (with suppositories), laxative dependence, protein-losing enteropathy

Metabolic: hypokalemia, fluid and electrolyte imbalances, tetany, alkalosis

Musculoskeletal: muscle weakness (with excessive use)

Interactions

Drug-drug.Antacids: gastric irritation, dyspepsia

Drug-diagnostic tests.Calcium, magnesium, potassium: decreased levels

Phosphate, sodium: increased levels

Drug-food.Dairy products: gastric irritation

Patient monitoring

• Assess stools for frequency and consistency.
• Monitor patient for electrolyte imbalances and dehydration.

Patient teaching

• Instruct patient to swallow (not chew) enteric-coated tablets no sooner than 1 hour before or after ingesting antacids or dairy products. Tell him not to chew tablets.
• Advise patient not to use bisacodyl or other laxatives habitually because this may lead to laxative dependence.
• Suggest other ways to prevent constipation, such as by eating more fruits, vegetables, and whole grains to increase dietary bulk and by drinking 8 to 10 glasses of water daily.
• As appropriate, review all other significant and life-threatening adverse reactions and interactions, especially those related to the drugs, tests, and foods mentioned above.

Dulcolax

(dŭl′kō-lăks′)
A trademark for an over-the-counter laxative containing bisacodyl.

Dulcolax

a trademark for a stimulant laxative (bisacodyl).

bisacodyl

A laxative used to manage constipation, especially in the elderly, as well as neurogenic bowel dysfunction.

Mechanism
Enteric nerve stimulation, increases fluid and salt secretion.
References in periodicals archive ?
First, phenolphthalein was removed from the market and was replaced by bisacodyl (28), which is now the active ingredient in over-the-counter laxatives such as Correctol and Ex-Lax and is also available as Dulcolax.
For example, on one randomly chosen night (January 13, 2004), the CBS Nightly News contained commercials for the following products: Pepto Bismol, Ambien, Ex-Lax, Pepcid Complete, Imitrex, Ester-C, Dulcolax, Maalox, Wellbutrin XL, Detrol LA, and Benefiber.
He was taking digoxin, captopril, warfarin, insulin, hydrocodone, dulcolax, hydrochiorothiazide-triamterene, and milk of magnesia.
Never allowing irritant laxative use, as there is an increased risk of laxative habit, toxic megacolon and possibly GI cancer in long-term users of drugs such as Dulcolax, Ex-Lax, Per-Diem, Senokot and other irritant laxatives.
As the #1 doctor-recommended stimulant for constipation relief, Dulcolax [R] reminds everyone over the age of 50 or with a family history of colon cancer, that a colonoscopy can save lives.
STIMULANTS (like Correctol, Dulcolax, Purge, Feen-A-Mint, and Senokot) cause rhythmic muscle contractions in the intestines.
5, Dulcolax supp prn Maalox 30 cc per NG for pH <5 Lacrilube OU prn KCL 10 meq in 25cc D5W over 1 hour x 3 for K < 3.
Dulcolax, Buscopan and Antistax," said Dr Alessandro Banchi, Chairman of the Board of Managing Directors at Boehringer Ingelheim and responsible for Marketing and Sales.
It provides a comprehensive consumer profile of the entire laxatives segment (minimum category sample = 5225 consumers), as well as a detailed segmentation by brand, namely: Black Forest, Brooklax, Dulcolax, Freshen, Hamburg Tea, Laxa-Dor, Puritone, Senokot, Surge and Super Tabs.
Repeat Brand of the Year Awards For TUMS, Vicks, FiberCon, Tylenol PM and Walgreens; Dulcolax and Tylenol Pain Reliever are at the top of their respective categories for the first time
If that isn't enough Dulcolax Balance[R] works with the water you drink to help restore your body's natural balance.
When combined with our Dulcolax line of products, the Zantac brand will provide Boehringer Ingelheim with significant additional market presence in the OTC GI product space," said Patrick Hennig, vice president of Sales & Marketing, Consumer Health Care, a division of Boehringer Ingelheim Pharmaceuticals, Inc.