Duffy blood group


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Duffy blood group

a red blood cell ANTIGEN found in certain human racial groups, controlled by a single autosomal gene on chromosome 1. Around 65% of Caucasians and 99% of Chinese are positive for the antigen being either homozygous or heterozygous for the allele Fy+, while 92% of West Africans are not, being homozygous for Fy- alleles.

Duffy,

surname of the patient in whom this antigen was first found in 1950.
Duffy antigen - may be related to resistance to malarial infection.
Duffy blood group
References in periodicals archive ?
The study, which genotyped and serotyped more than 4,000 blood donors for the Kell, Kidd, and Duffy blood group systems, observed a concordance of more than 99% between serotyping and genotyping.
Our study conclusively shows that the MassARRAY System and our genotyping assay designs can correctly predict the Kell, Kidd, and Duffy blood groups for greater than 99% of all Swiss blood donors.
The observation by Miller et al (7) that human erythrocytes lacking the Duffy blood group antigens are refractory to invasion by P.
He has also worked in the genetics of human blood groups and discovered the existence of Fy6, and allele of the Duffy blood group system that serves as the receptor for the binding of P.
The Duffy blood group system in human has been well-characterized.