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ductal carcinoma in situ

   Also found in: Dictionary/thesaurus, Acronyms, Encyclopedia, Wikipedia, Hutchinson 0.01 sec.
carcinoma /car·ci·no·ma/ (kahr″sĭ-no´mah) pl. carcinomas, carcino´mata   a malignant new growth made up of epithelial cells tending to infiltrate surrounding tissues and to give rise to metastases.
acinar carcinoma , acinic cell carcinoma, acinous carcinoma a slow-growing malignant tumor with acinic cells in small glandlike structures, usually in the pancreas or salivary glands.
adenocystic carcinoma , adenoid cystic carcinoma cylindroma; carcinoma marked by cylinders or bands of hyaline or mucinous stroma separating or surrounded by nests or cords of small epithelial cells, occurring particularly in the salivary glands.
adenosquamous carcinoma 
2. a diverse category of bronchogenic carcinoma, with areas of glandular, squamous, and large-cell differentiation.
adnexal carcinoma  that arising from, or forming structures resembling, the cutaneous appendages, particularly the sweat or sebaceous glands.
adrenocortical carcinoma  a malignant adrenal cortical tumor that can cause endocrine disorders such as Cushing's syndrome or adrenogenital syndrome.
alveolar carcinoma  bronchioloalveolar c.
ameloblastic carcinoma  a type of ameloblastoma in which malignant epithelial transformation has occurred, with metastases usually resembling squamous cell carcinoma.
apocrine carcinoma 
1. carcinoma of an apocrine gland.
2. a rare breast malignancy with a ductal or acinar growth pattern and apocrine secretions.
basal cell carcinoma  an epithelial tumor of the skin that seldom metastasizes but has the potential for local invasion and destruction; it usually occurs as one or several small pearly nodules with central depressions on the sun-exposed skin of older adults.
bronchioloalveolar carcinoma  a variant type of adenocarcinoma of the lung, with columnar to cuboidal cells lining the alveolar septa and projecting into alveolar spaces.
bronchogenic carcinoma  any of a group of carcinomas of the lung, so called because it arises from the epithelium of the bronchial tree.
cholangiocellular carcinoma  a rare primary carcinoma of the liver originating in bile duct cells.
chorionic carcinoma  choriocarcinoma.
clear cell carcinoma 
1. see under adenocarcinoma.
colloid carcinoma  mucinous c.
cribriform carcinoma 
2. an adenoid cystic carcinoma of the lactiferous ducts, one of the subtypes of ductal carcinoma in situ.
ductal carcinoma in situ  (DCIS) any of a large group of in situ carcinomas of the lactiferous ducts.
embryonal carcinoma  a highly malignant, primitive form of carcinoma, probably of germinal cell or teratomatous derivation, usually arising in a gonad.
carcinoma en cuirasse  carcinoma of the skin manifest as areas of thickening and induration over large areas of the thorax, frequently as a result of metastasis from a primary breast lesion.
endometrioid carcinoma  that characterized by glandular patterns resembling those of the endometrium, occurring in the uterine fundus and ovaries.
epidermoid carcinoma  squamous cell c.
carcinoma ex mixed tumor , carcinoma ex pleomorphic adenoma a type of malignant pleomorphic adenoma usually occurring in the salivary glands of older adults; an epithelial malignancy arises in a preexisting mixed tumor.
follicular carcinoma of thyroid gland  a type of thyroid gland carcinoma with many follicles.
hepatocellular carcinoma  primary carcinoma of the liver cells; it has been associated with chronic hepatitis B virus infection, some types of cirrhosis, and hepatitis C virus infection.
carcinoma in si´tu  a neoplastic entity wherein the tumor cells are still confined to the epithelium of origin, without invasion of the basement membrane; the likelihood of subsequent invasive growth is presumed to be high.
intraductal carcinoma 
1. any carcinoma of the epithelium of a duct.
Hürthle cell carcinoma  a malignant Hürthle cell tumor.
inflammatory carcinoma of the breast  a highly malignant carcinoma of the breast, with pink to red skin discoloration, tenderness, edema, and rapid enlargement.
large cell carcinoma  a bronchogenic tumor of undifferentiated (anaplastic) cells of large size.
invasive lobular carcinoma  an invasive type of carcinoma of the breast characterized by linear growth into desmoplastic stroma around the terminal part of the lobules of the mammary glands; usually developing from lobular carcinoma in situ.
lobular carcinoma 
lobular carcinoma in situ  (LCIS) a type of precancerous neoplasia found in the lobules of mammary glands, progressing slowly, sometimes to invasive lobular carcinoma after many years.
medullary carcinoma  that composed mainly of epithelial elements with little or no stroma; commonly occurring in the breast and thyroid gland.
meningeal carcinoma  primary or secondary carcinomatous infiltration of the meninges, particularly the pia and arachnoid.
Merkel cell carcinoma  a rapidly growing malignant dermal or subcutaneous tumor occurring on sun-exposed areas in middled-aged or older adults and containing irregular anastomosing trabeculae and small dense granules typical of Merkel cells.
mucinous carcinoma  adenocarcinoma producing significant amounts of mucin.
mucoepidermoid carcinoma  a malignant epithelial tumor of glandular tissue, particularly the salivary glands, characterized by acini with mucus-producing cells and by malignant squamous elements.
nasopharyngeal carcinoma  a malignant tumor arising in the epithelial lining of the nasopharynx, seen most often in people of Chinese ancestry. The Epstein-Barr virus has been implicated as a causative agent.
non–small cell carcinoma , non–small cell lung carcinoma (NSCLC) a general term comprising all lung carcinomas except small-cell carcinoma.
oat cell carcinoma  a form of small cell carcinoma in which the cells are round or elongated, have scanty cytoplasm, and clump poorly.
papillary carcinoma  carcinoma in which there are papillary excrescences.
renal cell carcinoma  clear cell carcinoma; carcinoma of the renal parenchyma, composed of tubular cells in varying arrangements.
scirrhous carcinoma  carcinoma with a hard structure owing to the formation of dense connective tissue in the stroma.
sebaceous carcinoma  carcinoma of the sebaceous glands, usually occurring as a hard yellow nodule on the eyelid.
carcinoma sim´plex  an undifferentiated carcinoma.
signet-ring cell carcinoma  a highly malignant mucus-secreting tumor in which the cells are anaplastic, with nuclei displaced to one side by a globule of mucus.
small cell carcinoma , small cell lung carcinoma (SCLC) a common, highly malignant form of bronchogenic carcinoma in the wall of a major bronchus, usually in middle-aged smokers, composed of small, oval, undifferentiated hematoxyphilic cells.
spindle cell carcinoma  carcinoma, usually of the squamous cell type, marked by fusiform development of rapidly proliferating cells.
squamous cell carcinoma 
1. an initially local carcinoma developed from squamous epithelium and characterized by cuboid cells and keratinization.
2. the form occurring in the skin, usually originating in sun-damaged areas or preexisting lesions.
3. a form of bronchogenic carcinoma, usually in middle-aged smokers, generally forming polypoid or sessile masses obstructing the bronchial airways.
terminal duct carcinoma  a slow-growing, locally invasive, malignant neoplasm composed of myoepithelial and ductal elements, occurring in the minor salivary glands.
transitional cell carcinoma  a malignant tumor arising from a transitional type of stratified epithelium, usually affecting the urinary bladder.
tubular carcinoma 
1. an adenocarcinoma in which the cells are arranged in the form of tubules.
2. a type of breast cancer in which small glandlike structures are formed and infiltrate the stroma, usually developing from a ductal carcinoma in situ.
verrucous carcinoma  a variety of locally invasive squamous cell carcinoma with a predilection for the buccal mucosa but also affecting other oral soft tissues and the larynx; sometimes used for the similar Buschke-Löwenstein tumor on the genitals.

ductal carcinoma in situ
Intraductal carcinoma, DIN 3 Surgical oncology A localized form of breast CA, in which malignant cells are confined to the duct wall; DCIS has a heterogeneous biologic behavior and morphology, and is detectable by mammography Epidemiology DCIS has ↑–2/105–1973 to 14/105–1992; it accounts for 12% of breast CAs–US Subtypes 1. Low nuclear grade without central necrosis–low to minimal risk of recurrence after wide excision 2. High nuclear grade with central necrosis–high recurrence despite RT and complete–conservative excision Management Lumpectomy, lumpectomy with RT, or by mastectomy

Patient discussion about ductal carcinoma in situ.

Q. Hi all. I was diagnosed with DCIS in April. Had a lumpectomy about 3 cm and it was removed. Am I cured fully? Hi all. I was diagnosed with DCIS in April. Had a lumpectomy about 3 cm and it was removed. I then had 28 radiation and 4 boosters. I went to the cancer center for my checkup and the doctor said nothing to worry. They didn’t advice me further follow up and I am normal for the past 6 months and not even taking tamoxifen. I am quite normal like others. Am I cured fully?

A. Hey nothing to worry!! Early diagnosis is half cured. The same thing applies to your case. With early diagnosis and treatment, the doctors should have removed the cancer parts with the surgery. Based on the report they have given you radiation and other meds. If you be estrogen +ve then they would have given you it as a preventive. By the way if you have any doubts better approach your doctor and have your checkup done as a precautionary measure.

Q. My wife is diagnosed with DCIS type of breast cancer. My wife is diagnosed with DCIS type of breast cancer. Doctors had staged my wife`s cancer as low. She is still due for some tests which she will soon have. Doctor have told that there is nothing much to worry so why are they taking so many tests?

A. All the tests are taken to confirm about the type of treatment to be given. These pre treatment tests can avoid the risk of post treatment complications. Even if the complications arise they will know the best possible course of counter treatment. So please cooperate with the doctor.
http://www.youtube.com/watch?v=y2kl_eOWEtc&eurl=http://www.imedix.com/health_community/vy2kl%5EeOWEtc_nurse_sandy_interview_1_breast_cancer?q=dcis%20type%20of%20b&feature=player_embedded

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Led by Visiting Professor James Lawson at UNSW, the researchers confirmed the presence of high-risk HPV in the nuclei of breast cancer epithelial cells in five (39 per cent) of 13 ductal carcinoma in situ and three (21 per cent) of 14 invasive ductal carcinoma (IDC) breast cancer specimens.
I had DCIS, ductal carcinoma in situ, which is apparently quite common.
Because breast cancer presents in different ways, there are a number of treatment options, depending on whether a patient has non-invasive cancer--called ductal carcinoma in situ (DCIS)--or metastatic cancer, which has spread outside the breast.
 
 
 
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