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Drug interaction
(redirected from Drug-drug interaction)

    Also found in: Acronyms, Wikipedia 0.02 sec.
drug in·ter·ac·tion (ntr-kshn)
n.
The pharmacological result, either desirable or undesirable, of drugs interacting with themselves or with other drugs, with endogenous chemical agents, with components of the diet, or with chemicals used in or resulting from diagnostic tests.
Drug interaction
A chemical or physiological reaction that can occur when two different drugs are taken together.
Mentioned in: Interactions
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? Mentioned in ? References in periodicals archive
 
While small prospective studies have not revealed any significant drug-drug interaction between warfarin and levofloxacin, several case reports have indicated that levofloxacin may significantly potentiate the anticoagulation effect of warfarin.
Interaction between warfarin and levofloxacin: case series by Vadlamudi, Raja S.; Smalligan, Roger D.; Ismail, Hassan M. / Southern Medical Journal
On January 31 the FDA announced that the Sustiva (efavirenz) package insert had been changed "to include drug-drug interaction information regarding coadministration of efavirenz with rifampin, diltiazem, itraconazole, voriconazole, atorvastatin, pravastatin, simvastatin, pimozide and bepridil.
Sustiva: revised drug-interaction information by AIDS Treatment News
The reduced protein binding capacity may lead to a greater potential for drug-drug interaction via competitive displacement from the limited number of serum binding sites (Girgis and Brooks 1994).
Pharmacokinetic and pharmacodynamic factors that can affect ... by Sonawane, Babasaheb / Environmental Health Perspectives
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