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drug allergy |
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allergy /al·ler·gy/ (al´er-je) a hypersensitive state acquired through exposure to a particular allergen, reexposure bringing to light an altered capacity to react. See hypersensitivity. aller´gic atopic allergy atopy. bacterial allergy specific hypersensitivity to a particular bacterial antigen. bronchial allergy atopic asthma; see asthma. cold allergy a condition manifested by local and systemic reactions, mediated by histamine, which is released from mast cells and basophils as a result of exposure to cold. contact allergy see under dermatitis . delayed allergy see under hypersensitivity. drug allergy an allergic reaction occurring as the result of unusual sensitivity to a drug. food allergy , gastrointestinal allergy allergy produced by ingested antigens in food, usually manifested by a skin reaction. hereditary allergy atopy. immediate allergy see under hypersensitivity. latent allergy that not manifested by symptoms but which may be detected by tests. physical allergy a condition in which the patient is sensitive to the effects of physical agents, such as heat, cold, light, etc. pollen allergy hay fever. polyvalent allergy see pathergy (2). spontaneous allergy atopy. drug allergy, hypersensitivity to a pharmacologic agent. Manifestions range from a mild rash to anaphylactic shock, depending on the dose, and the allergen sensitivity of the individual. The primary drug that produces allergy is penicillin. Others include aspirin, phenylbutazone, novobiocin, other antibiotics, and radiopaque contrast media containing iodine. See also anaphylactic shock. allergy an altered reactivity following second or subsequent exposure to antigen (allergen). See also hypersensitivity, allergic. atopic allergy hereditary predisposition to develop certain allergies. See atopy. bacterial allergy a specific hypersensitivity to a particular bacterial antigen, e.g. Mycobacterium tuberculosis; it is dependent on previous infection with the specific organism. bronchial allergy asthma. cold allergy a condition manifested by local and systemic reactions, mediated by histamine, which is released from mast cells and basophils as a result of exposure to cold. delayed allergy see delayed hypersensitivity. drug allergy see drug allergy. drying-off allergy see milk allergy (below). food allergy called also gastrointestinal allergy; see food hypersensitivity. gastrointestinal allergy see food allergy (above). hereditary allergy an allergy with a hereditary predisposition. The tendency to develop some forms of allergy is inherited, but the specific clinical form is not. IgE, formerly called reagin or reaginic antibody, may be involved. See also atopy. induced allergy allergy resulting from the injection of an antigen, contact with an antigen, or infection with a microorganism, as contrasted with hereditary allergy. inhaled allergy see atopy. milk allergy a hypersensitivity to the milk protein, α-casein. Signs, varying from urticaria to anaphylaxis, have occurred in Jersey cows when milk escapes from the udder into the bloodstream during the drying off period. physical allergy a condition in which physical agents, such as heat, cold or light, trigger an allergic response. drug 1. any medicinal substance. 2. a narcotic. 3. to administer a drug. drug administration includes aerosol, oral, transtracheal infusion, subcutaneous, intramuscular, intravenous, intrauterine, intraperitoneal, intra-articular, intramammary, intrathecal, subconjunctival, percutaneous, percutaneous intraruminal, gas inhalation. Mass medication is per feed or drinking water or, in the case of captive fish, in the tank water. For feral animals individual dosing by projectile dart is usual, for group therapy administration by bait is possible. drug allergy immune-mediated hypersensitivity to a drug molecule. Includes anaphylaxis, cutaneous reaction. animal drug a drug specifically tested for, and recommended for use in, animals. A legal point of importance if an animal dies as a result of an unusual or allergic reaction to medication with a drug not licensed for use in animals. drug augmented swine dysentery pigs receiving prophylactic medication are more severely affected than untreated pigs. bactericidal/bacteriostatic drug see antibiotic. drug binding binding of a drug to a large molecule in the tissues or fluids, e.g. binding to protein in the blood, may affect the metabolism of the drug, especially its rate of excretion. chemotherapeutic drug see chemotherapy. drug combinations a pharmaceutical strategy of combining several drugs into one formulation to provide for a specific requirement, e.g. an antibiotic combined with an anti-inflammatory agent in a mastitis ointment. Has the disadvantage that the dose of one drug is determined by the dose of the other. controlled drug availability and use of the drug is controlled by law. The control is at various levels of severity depending on the degree of danger associated with the uncontrolled use of each drug. drug delayed swine dysentery swine dysentery appears several days after treatment is discontinued. drug delayed-augmented swine dysentery after successful treatment during an attack of swine dysentery a more severe form of the disease occurs after treatment ceases. drug diminished swine dysentery the disease is reduced in severity as a result of treatment but is not eliminated. drug eruption an eruption or solitary skin lesion caused by a drug. See also dermatitis medicamentosa. drug hypersensitivity see drug allergy (above). mutagenic d's those that affect the DNA of the target organism have the hazard of creating new races of microorganisms with increased pathogenicity. drug residue the amount of the drug that can be detected in tissues at specified times after administration of the drug ceases. See also drug tolerance (below). drug resistance said mainly of antibacterial drugs and of microorganisms that are unaffected by the drug whilst most organisms of its species are susceptible. The resistance may be inherent or secondary to frequent exposure at sublethal levels. Resistance of an animal to a specific drug, e.g. to insulin, can also occur in this way. drug resistant swine dysentery medication of the feed is not an effective procedure and diarrhea and deaths occur. drug safety margin the magnitude of the difference between the dose required to produce a maximum therapeutic effect and that which produces a toxic effect. Registering authorities require this information. drug selectivity capacity to produce a single effect. teratogenic drug produces a toxic effect on the fetus at a particular phase of development producing a malformation. drug allergy An immune response to a therapeutic. See Allergy. Patient discussion about drug allergy. Q. I am worried about the allergic reactions I had from the Chinese herbal drug. I am worried about the allergic reactions I had from the Chinese herbal drug that I took for my arthritis…..are these safe? A. Many people have some type of reaction to either a drug and even a supplement. You can check with your doc to get tested to see what your sensitivities are. Regarding arthritis, no milk, cheese, yogurt, butter, anything with milk for starters, AVOID like the plague! Suagr consumption too will raise hell with it. There is a product that someone I knew took, called, "Cell Guard" which he bought at a health food store or Whole Foods. After a couple of months, he was pain free. Its worth a try! Cell Guard is made with SOD or "superoxide dismutase" Read more or ask a question about drug allergyStudies have shown that SOD can play a critical role in reducing internal inflammation and lessening pain associated with conditions such as arthritis! Check it out! Let me know how you do! 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Oral amiodarone was given cautiously to the patient without incident, and he was discharged on 200 mg twice daily with no signs of a drug allergy. Either these patients had misreported the drug allergy, or it had worn off over the years. With e-prescribing, physicians and their office staffs will benefit from access to online information about potential hazardous drug-to-drug interactions and drug allergy reactions, making it easier to prescribe the right drug, with the proper dosage, the first time. |
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