doxorubicin

(redirected from Doxorubicin-induced cardiomyopathy)
Also found in: Dictionary, Thesaurus, Wikipedia.

doxorubicin

 [dok″so-roo´bĭ-sin]
an antitumor antibiotic that binds to DNA, inhibits synthesis of nucleic acids, and inhibits cell division. It has one of the widest spectrums of antitumor activity of any antineoplastic agent and is administered intravenously as the hydrochloride salt. Side effects include bone marrow depression, alopecia, and cardiac toxicity; electroencephalogram monitoring is required during its administration. A liposome-encapsulated preparation of the hydrochloride salt is used in the treatment of Kaposi's sarcoma associated with acquired immunodeficiency syndrome (AIDS).

dox·o·ru·bi·cin

(doks'ō-rū'bi-sin),
An antineoplastic antibiotic isolated from Streptomyces peucetius; also used in cytogenetics to produce Q-type chromosome bands.
Synonym(s): adriamycin

doxorubicin

/doxo·ru·bi·cin/ (dok″so-roo´bĭ-sin) an antineoplastic antibiotic, produced by Streptomyces peucetius, which binds to DNA and inhibits nucleic acid synthesis; used as the hydrochloride salt and as a liposome-encased preparation of the hydrochloride salt.

doxorubicin

(dŏk′sə-ro͞o′bĭ-sĭn)
n.
An antibiotic obtained from the bacterium Streptomyces peuceticus, used as an anticancer drug.

ABDIC

A "salvage" chemotherapy regimen used for patients who have a disease—e.g., lymphoma—relapse after radiation therapy or chemotherapy.

doxorubicin

Adriamycin Oncology An anthracycline antibiotic used for leukemias, lymphomas, sarcomas, solid tumors Adverse effects BM suppression, alopecia, vomiting, stomatitis, dose-dependent cardiomyopathy. See Chemotherapy.

dox·o·ru·bi·cin

(doks'ō-rū'bi-sin)
An antineoplastic antibiotic isolated from Streptomyces peucetius; also used in cytogenetics to produce Q-type chromosome bands.
Synonym(s): adriamycin.

doxorubicin

An antibiotic, also known as Adriamycin, that interferes with the synthesis of DNA and is thus useful an an anticancer agent. It has many side effects including loss of hair, sickness and vomiting, interference with blood production and heart damage. The drug is on the WHO official list. A brand name is Caelyx.

doxorubicin

an antineoplastic antibiotic, which binds to DNA and inhibits synthesis of nucleic acids and cell division. It is used intravenously to produce regression in various neoplastic conditions. The side-effects include bone marrow depression, alopecia and cardiac toxicity. Called also adriamycin. See also anthracycline antibiotic.