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Benzylisoquinolinium compounds, such as d-tubocurarine, metocurine, doxacurium, atracurium, and mivacurium, are more likely to cause direct mast cell degranulation than aminosteroid compounds such as pancuronium, vecuronium, rocuronium, and pipecuronium.
Agents such as vecuronium, doxacurium, and cisatracurium have minimal effects.
Strangely, doxacurium is included in the muscle relaxant section and not with the other neuromuscular blocking drugs.
Other agents include cistracurium, doxacurium and mivacurium, all of which have onsets within a few minutes and can last for about an hour.