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down-regulation
(redirected from Downregulation)

    Also found in: Wikipedia 0.02 sec.
down-regulation /down-reg·u·la·tion/ (doun reg-u-la´shun) a decrease in the number of receptors for a chemical or drug on cell surfaces in a given area, usually due to long-term exposure to the agent.
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Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage.
Lead increases lipopolysaccharide-induced liver injury through tumor ... by Liu, Ming-Yie / Environmental Health Perspectives
The pYV plasmid-encoded Yop proteins have been implicated in lymphocyte suppression through downregulation of co-stimulatory molecules (13) and impairment of nitric oxide, tumor necrosis factor (TNF)-[alpha], and proinflammatory cytokine production (14).
Yersinia pseudotuberculosis septicemia and HIV by Visca, Paolo / Emerging Infectious Diseases
The idea behind this device is that patients will experience downregulation of the hyperstimulation that is associated with increased emotions and increased habituation.
The relationship of tinnitus, hyperacusis, and hearing loss by Chen, Kejian / Ear, Nose and Throat Journal
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