doubly labeled water

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doub·ly la·bel·ed wa·ter

(dŭb'lē lā'bĕld waw'tĕr)
Noncalorimetric technique for measuring energy expenditure in free-living subjects using an oral dose of water containingstable nonradioactive isotopes, 2H and 18O. Derived CO2 production is used to calculate energy expenditure using indirect calorimetry formulas.
References in periodicals archive ?
This study is among the first to use the doubly-labeled water method (the industry gold standard) to evaluate the validity of body monitoring devices in children.
7) Doubly-labeled water is considered the gold standard in the measurement of energy expenditure and is commonly used to validate other methods.
The doubly-labeled water method is particularly useful for measuring average metabolic rate over relatively long periods of time (i.