Double Bubble Sign

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Double Bubble Sign

A radiologic finding in which there are 2 distinct gas pockets in an upper GI radiocontrast study, seen in those with atresia of the 2nd segment of the duodenum, 20–30% of whom have Down syndrome; the larger left bubble corresponds to gastric gas; the smaller right bubble corresponds to gas in the duodenal bulb. The double bubble sign may also occur in an annular pancreas with/without duodenal atresia, duodenal stenosis, peritoneal bands and volvulus. The sign is correspondingly smaller if there is passage of air

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