dose-response relationship


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dose-·re·sponse re·la·tion·ship

relationship in which a change in the amount, intensity, or duration of exposure is associated with a change in risk of a specified outcome.

dose-response relationship

a mathematic relationship between the dose of a drug or radiation and the body's reaction to it. In a linear dose-response relationship, the response is proportional to the dose. Thus, if the dose is doubled, the response is also doubled. In a linear nonthreshold relationship, any dose, regardless of size, can theoretically cause a response.

dose-re·sponse re·la·tion·ship

(dōs rē-spons' rē-lā'shŭn-ship)
Direct association between a stimulus and a desired outcome (e.g., quantity of physical activity and good health).
References in periodicals archive ?
We see a dose-response relationship between frequency of night shift work and Type 2 diabetes, where the more often people do shift work, the greater their likelihood of having the disease, regardless of genetic predisposition,' said Ceiine Vetter, Professor at the University of Colorado-Boulder.
Symptom improvement was observed after one week with intranasal esketamine for all three doses (28 mg, 56 mg and 84 mg), administered twice weekly, with a significant ascending dose-response relationship (p
The new results show a clear dose-response relationship between opioid dose and risk of overdose among Medicaid patients with noncancer pain, according to Dr.
Dose-response relationship between cigarette smoking and female sexual dysfunction.
A team of researchers based in France and Canada set out to investigate the relationship between the risk of Alzheimer's disease and exposure over a several years, as well as a potential dose-response relationship.
There is a strong dose-response relationship between percentage weight loss and improvement in knee pain, function, symptoms, sport or recreation, and quality of life," Dr.
Dose-response relationship was assessed by restricted cubic spline.
There was a significant dose-response relationship between increasing volunteerism prior to medical school and greater interest in practicing medicine among vulnerable populations.
This study investigated the dose-response relationship between breastfeeding duration and cognitive development in French preschool children.
My hope was that those with a special interest in a particular risk factor would be stimulated to provide stronger data on either the exposure distribution or the dose-response relationship so that the calculations could be refined.
The protective effect of aspirin use appears robust because the analyses suggests a dose-response relationship in which high-dose aspirin was significantly associated with decreased Barrett's esophagus risk," said Chin Hur, MD, MPH, of the Massachusetts General Hospital Institute for Technology Assessment and lead author of this study.
Investigators found evidence of a dose-response relationship between TZDs and fracture risk.