antidopaminergic

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antidopaminergic

adjective Preventing or countering dopamine effects.
References in periodicals archive ?
Researchers have also found that an acute dose of dopamine antagonist haloperidol reduced the amplitude of the ERG in humans (Holopigian et al.
APD421 comprises a low dose intravenous formulation of the marketed dopamine antagonist amisulpride, which Acacia Pharma has repurposed for the completely new, patent-protected use of management of PONV.
Domperidone is a dopamine antagonist that cannot cross the blood-brain barrier, so is useful for limiting non-motor symptoms and dopaminergic drug effects.
Breast-feeding women should not take the dopamine antagonist domperidone to induce or increase lactation, because the drug may put them at risk of developing a fatal cardiac arrhythmia, the Food and Drug Administration has warned.
Testing with the dopamine antagonist, domperidone, (10 mg, administered intravenously) produced a normal increase in serum prolactin 30 min after administration (basal prolactin, 663 mIU/L, increasing to 5220 mIU/L; prolactin measured at our endocrine center).
APD403 is a novel and proprietary product containing the dopamine antagonist amisulpride, which Acacia Pharma is also developing as APD421 for the prevention and treatment of post-operative nausea & vomiting (PONV).
Dopamine antagonist drugs may act centrally, or can increase gastric emptying and contraction of the gastro-oesophageal sphincter to reduce nausea, reflux and vomiting.
5) Dopamine release was defined as amphetamine-induced changes in the ability of the dopamine antagonist raclopride to bind to dopamine receptors.
If nausea is present or if the pain is escalating, then the patient can add a dopamine antagonist, but no more than twice a week; these drugs are helpful in treating pain and also speed up NSAID absorption.
Data generated by Acacia Pharma in Phase 2 and Phase 3 clinical trials indicate that APD421, its proprietary low dose intravenous formulation of the marketed dopamine antagonist amisulpride, is an effective, safe anti-emetic.
In a double-blind, placebo-controlled laboratory study, 16 subjects diagnosed with either alcohol abuse or alcohol dependence reported less craving for alcohol and consumed less of their preferred alcoholic beverage after receiving the dopamine antagonist haloperidol (Haldol(r)), a medication commonly prescribed to treat severe psychiatric illness (Modell et al.
Our clinical data indicate APD421 is an effective dopamine antagonist antiemetic, which has the potential to become a mainstay of therapy, contributing greatly to the well-being of patients following surgery.