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dopamine
(redirected from Dopamine agonist)

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia 0.03 sec.
dopamine /do·pa·mine/ (-mēn) a catecholamine formed in the body by the decarboxylation of dopa; it is an intermediate product in the synthesis of norepinephrine, and acts as a neurotransmitter in the central nervous system. The hydrochloride salt is used to correct hemodynamic balance in the treatment of shock and is also used as a cardiac stimulant.
do·pa·mine (dp-mn)
n.
A monoamine neurotransmitter formed in the brain by the decarboxylation of dopa and essential to the normal functioning of the central nervous system. A reduction in its concentration within the brain is associated with Parkinson's disease. Also called 3-hydroxytyramine.

Dopamine
A neurochemical made in the brain that is involved in many brain activities, including movement and emotion.

DOPamine
[dō′pəmin]
a naturally occurring sympathetic nervous system neurotransmitter that is the precursor of norepinephrine. It is produced in the substantia nigra and transmitted to the putamen and caudate nucleus. It has an inhibitory effect on movement. A depletion of dopamine produces the symptoms of rigidity, tremors, and bradykinesia that are characteristic of Parkinson's disease. It is available as an intravenously injectable drug. DOPamine has potent dopaminergic, beta-adrenergic, and alpha-adrenergic receptor activity. See also DOPamine hydrochloride.

dopamine [do´pah-mēn]
a compound produced by the decarboxylation of dopa; it is the direct precursor in the synthesis of norepinephrine and is also a neurotransmitter in the central nervous system. It is administered intravenously to correct hemodynamic imbalance in persons with shock because it increases blood pressure, especially systolic pressure, as well as urinary output; it is also used as a cardiac stimulant.

dopamine (dōˑ·p·mēn),
n a neurochemical that supports fine motor activity, blood pressure, focus, inspiration, intuition, enthusiasm, and joy, among other functions.

dopamine
(dō´pmēn´),
n a sympathomimetic catecholamine used in the treatment of shock, hypotension, and low cardiac output.

dopamine
a compound, hydroxytyramine, produced by the decarboxylation of dopa; an intermediate product in the synthesis of norepinephrine. It is a neurotransmitter in the central nervous system; administered intravenously to correct hemodynamic imbalance in shock syndrome.

dopamine agonist
used to terminate pregnancy. See bromocriptine, cabergoline.
dopamine β-hydroxylase
enzyme catalyzing the synthesis of norepinephrine from dopamine. A copper-containing mono-oxygenase requiring vitamin C (ascorbic acid).

dopamine
Neurology A catecholamine hormone and neurotransmitter essential to CNS activity; it is involved motor control, cognition, and reward; abnormal dopamine levels occur in Parkinson's disease, paranoia, memory and concentration defects; dopamine may modulate endorphin levels, altering perception of pain and pleasure; it restricts prolactin, affecting libido See Biogenic amine, Catecholamine, Indolamine, Serotonin.


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Gluck said that an increased sensitivity to learning from events that results in positive outcomes, coupled with a decrease in the ability to learn from negative outcomes, could explain why some Parkinson patients treated with dopamine agonists develop impulse-control disorders, including pathological gambling, hypersexuality, alcoholism, and compulsive eating and shopping.
CHICAGO -- In a group of patients with motor fluctuations and dopamine agonist-related side effects, adding orally disintegrating selegiline and decreasing the dopamine agonist dose reduced these adverse events without worsening Parkinson's disease symptoms.
is a dopamine agonist that was first approved by the FDA for the treatment of Parkinson's disease in 1997, along with GlaxoSmithKline's similar drug Requip (ropinirole).
 
 
 
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