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A congenital form of dwarfism characterized by extreme growth retardation, endocrine disorders, and emaciation, with elfin facies and large, low-set ears; autosomal recessive inheritance; caused by mutation in the insulin receptor gene (INSR) on 19p.
[Irish leprechaun, elf]
A rare genetic disorder caused by severe insulin resistance and characterized by acanthosis nigricans, emaciation, endocrine disorders, hirsutism, and facial features dominated by large wide-set eyes and large low-set ears.
Donohue,William Leslie, Canadian pathologist, 1906-1985.
Donohue syndrome - Synonym(s): Donohue disease