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donepezil |
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donepezil /do·nep·e·zil/ (do-nep´ĕ-zil) an acetylcholinesterase inhibitor used as the hydrochloride salt for the treatment of mild to moderate symptoms of dementia of the Alzheimer type; administered orally. Donepezil A drug commonly prescribed for Alzheimer's disease that provides temporary improvement in cognitive functions for some patients with mild-to-moderate forms of the disease. Mentioned in: Dementia donepezil, a reversible cholinesterase. indication It is used to treat mild to moderate dementia in Alzheimer's disease. contraindications Known hypersensitivity to this drug or to piperidine derivatives prohibits its use. adverse effects Life-threatening effects include seizures and atrial fibrillation. Other adverse effects are dizziness, somnolence, fatigue, abnormal dreams, syncope, hypotension or hypertension, anorexia, urinary frequency, urinary tract infection, incontinence, rash, flushing, rhinitis, upper respiratory infection, cough, pharyngitis, cramps, and arthritis. Common side effects include insomnia, headache, nausea, vomiting, and diarrhea. donepezil Aricept® Neurology A cholinesterase inhibitor used to maintain cognition in Alzheimer's disease Contraindications Succinylcholine-type anesthesia, sick sinus syndrome, seizures Adverse events N&V, insomnia,
muscle cramps, anorexia, fatigue. See Alzheimer's disease. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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The National Institute for Health and Clinical Excellence (NICE) has decided to restrict access to donepezil, galantamine and rivastigmine to patients in the moderate stages of Alzheimer's disease. The study found a slower rate of progression among people who were given donepezil (Aricept), but only for the first year of the study. Donepezil (Aricept)--Approved for mild and moderate stages of Alzheimer's, patients using this drug may demonstrate clearer thinking and maintained physical function. |
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