domain (redirected from Domains)

domain /do·main/ (do-man´) in immunology, any of the homology regions of heavy or light polypeptide chains of immunoglobulins.

---

do·main (d-mn)

n.

One of the homologous regions that make up an immunoglobulin's heavy and light chains and serve specific immunological functions.

---

domain

1. region of a protein with a characteristic tertiary structure and function; homologous domains may occur on different proteins.

2. regions of the heavy chain of immunoglobulins. See cH domain, cL domain.

---

transmembrane domain

for any membrane-bound protein or glycoprotein, those amino acid sequences that traverse and are present in the cell membrane. In receptor biology, transmembrane domains are distinguished from the extracellular ligand binding domains, cytoplasmic domains, and from immunological domains.