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docusate

   Also found in: Wikipedia 0.08 sec.
docusate /doc·u·sate/ (dok´u-sāt) any of a group of anionic surfactants widely used as emulsifying, wetting, and dispersing agents; the calcium, potassium, and sodium salts are used as stool softeners.
docusate
[dok′yo̅o̅sāt]
a stool softener. Also called dioctyl calcium sulfosuccinate, dioctyl potassium sulfosuccinate, dioctyl sodium sulfosuccinate.
indication It is prescribed in the treatment of constipation.
contraindications Signs or symptoms of appendicitis, concomitant administration of mineral oil, or known hypersensitivity to the drug prohibits its use.
adverse effects No serious adverse reactions are known.


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1,12) Agents in current use or under evaluation include various formulations of oleic acid polypeptide complex, triethanolamine polypeptide, carbamide peroxide, olive oil, mineral oil, sodium bicarbonate, acetic acid, and docusate sodium.
An example of a stool softener is docusate sodium, which emulsifies fat in the gastrointestinal tract and, therefore, softens the stool.
PROSCAR (finasteride) tablets for oral administration are film-coated tablets that contain 5 mg of finasteride and the following inactive ingredients: hydrous lactose, microcrystalline cellulose, pregelatinized starch, sodium starch glycolate, hydroxypropyl cellulose LF, hydroxypropyl methylcellulose, titanium dioxide, magnesium stearate, talc, docusate sodium, FD&C Blue 2 aluminum lake and yellow iron oxide.
 
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