Whereas untreated HL-60 cells exhibit a typically nonadherent, fairly round morphology, cells exposed to this abietane diterpene
display condensation and fragmentation of chromatin which is detectable after only 4 h of treatment.
Caption: Kahweol, a diterpene
in coffee, inhibits angiogenesis, or blood vessel growth.
from Leucas aspera inhibiting prostaglandin-induced contractions.
are rare in floral scents and are only reported
Percolated, instant and drip filtered coffee have low or negligible levels of diterpenes
Unfiltered coffee also contains diterpenes
, cholesterol-raising substances, which are removed when coffee is filtered.
Previous research suggests the culprit might be a group of chemicals in coffee beans called diterpenes
Sweetening potencies of various diterpenes
found in Stevia rebaudiana are listed in Table 1.
He has developed processes integrating highly engineered microbes in industrial settings to produce amino acids, such as lysine and isoleucine; indandiol, an essential precursor of the AIDS drug Crixivan; and important diterpenes
, such as lycopene and taxadiene, a precursor to the cancer drug taxol.
Using invasion-inhibition-guide fractionation, we screened more than 200 constituents from these plants, including sesquiterpenes, diterpenes
, chalcones, and sesquiterpene lactones (data not shown).
Caballero (2004) evaluated the antifeedant activity caused by 3 groups of terpenoids (neoclerodane diterpenes
, neo-clerodane sesquiterpenes, and limonoids) against Spodoptera exigua Hubner and the coleopteran, Leptinotarsa decemlineata Say, with results that suggested to us that we would expect to identify an antifeedant effect caused by terpenes against S.
The patent is titled "Composition of Labdane diterpenes
extracted from Andrographis paniculata, useful for the treatment of autoimmune diseases, and Alzheimer Disease by activation for PPAR-Gamma receptors.