disulfiram (redirected from Disulfirum)

disulfiram /di·sul·fi·ram/ (di-sul´fi-ram) an antioxidant that inhibits the oxidation of the acetaldehyde metabolized from alcohol, resulting in high concentrations of acetaldehyde in the body. Used to produce aversion to alcohol in the treatment of alcoholism because extremely uncomfortable symptoms occur when its administration is followed by ingestion of alcohol.

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di·sul·fi·ram (d-slf-rm)

n.

An antioxidant used in the treatment of chronic alcoholism that interferes with the normal metabolic degradation of alcohol in the body, producing an unpleasant reaction when a small quantity of alcohol is consumed.

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disulfiram

(dīsul´fram´),
n brand name: Antabuse;
drug class: aldehyde dehydrogenase inhibitor;
action: blocks oxidation of alcohol at acetaldehyde stage;
uses: chronic alcoholism (as adjunct).