ganglioside /gan·glio·side/ (gang´gle-o-sīd) any of a group of glycosphingolipids found in the central nervous system tissues and having the basic composition ceramide-glucose-galactose-N -acetylneuraminic acid. The form GM1 accumulates in tissues in GM1 gangliosidoses and the form GM2 in GM2 gangliosidoses.
Ganglioside
ganglioside
gan·gli·o·side (g ng gl - -s d )n. Any of a group of glycosphingolipids chemically similar to the cerebrosides, found principally in the surface membrane of nerve cells and in the spleen. |
Ganglioside
A fatty (lipid) substance found within the brain and nerve cells.
Mentioned in: Tay-Sachs Disease
ganglioside
[gang′glē·əsīd′]
a glycosphingolipid found in the brain and other nervous system tissues. Gangliosides are members of a group of galactose-containing cerebrosides with a basic composition of ceramide-glucose-galactose-N-acetyl neuraminic acid. Accumulation of gangliosides caused by an inborn error of metabolism results in gangliosidosis or Tay-Sachs disease.
ganglioside
a class of galactose-containing cerebrosides found in central nervous system tissues; they are glycolipids of the basic composition ceramide-glucose-galactose-N-acetyl neuraminic acid. The form GM1 accumulates in tissues in generalized gangliosidosis as observed in Friesian cattle, dogs and cats. The form GM2 accumulates in a similar disease of Yorkshire pigs, dogs and cats.
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