directly observed therapy

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directly observed therapy (DOT),

visual monitoring by a health care worker of patients' ingestion of medications, to ensure compliance in difficult or long-term regimens, such as in oral treatment for tuberculosis; a contentious aspect of some WHO programs.

directly observed therapy

Therapeutics A strategy for ensuring Pt compliance with therapy, where a health care worker or designee watches the Pt swallow each dose of prescribed drugs. See Patient compliance. Cf Directed observation.

directly observed therapy



Oral administration of a drug or of drugs to a patient under supervision to ensure the drug is swallowed. DOT is esp. important in treating patients with infectious diseases (e.g., HIV/AIDS or tuberculosis) in which development of drug-resistant microorganisms is likely to threaten public health if the drug is not taken exactly as prescribed.
References in periodicals archive ?
Directly observed treatment of latent TB infection (DOPT), first introduced in the early 1990s in the aftermath of the highly successful use of directly observed therapy in TB cases, has now been implemented in a number of settings throughout the United States.
Under the DOTS strategy, free anti-TB drugs are supplied for the whole period of treatment through a well organized network and a TB patient swallows his/her daily dose under the direct observation of a trained health worker, hence the name Directly Observed Treatment.
He said more than 700,000 tuberculosis patients were treated free of charge while 100 percent coverage of WHO-recommended treatment strategy for detection and cure known as Directly Observed Treatment, Short-course (DOTS) is achieved in the country.
Dye and his colleagues reported that, with the exception of Africa and Eastern Europe, WHO can achieve its goals with increased application of the Directly Observed Treatment Scheme (DOTS), a public health strategy that includes gaining political commitment, detecting cases based on sputum smear microscopy, utilizing standard short-course therapy with supportive patient management, ensuring regular drug supplies, and standardizing systems for recording cases and reporting outcomes (JAMA 2005;293:2767-75).
the directly observed treatment short course [DOTS], the Roll Back Malaria initiative, the so-called 3 by 5 Initiative) are gender-sensitive.
ISLAMABAD -- Citizens on Thursday urged the management of public sector hospitals to properly implement the Directly Observed Treatment Short-course (DOTS) to support tuberculosis patients.
Watching patients take their medication is a strategy in the WHO's Directly Observed Treatment, Short-Course-Plus (DOTS-Plus) initiative.
ISLAMABAD -- Citizens on Sunday asked the authorities of public sector hospitals to properly implement the Directly Observed Treatment Short-course (DOTS) to support tuberculosis patients.
Expand and enhance Directly Observed Treatment Short-course (DOTS)
The Stop TB Partnership's Green Light Committee will use the grant to provide technical assistance and monitoring of TB interventions, including the directly observed treatment, short-course strategy -- called DOTS Plus -- for multi-drug resistant TB activities.
Since 1993, in response to this epidemic, the government of India has implemented the Revised National Tuberculosis Control Program, which is based on directly observed treatment (short course) principles (1).
Over the past year, USAID has expanded its efforts to promote directly observed treatment, short-course strategy (DOTS) for TB control, as well as efforts to combat TB and HIV co-infection.

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