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dipyrone

   Also found in: Wikipedia 0.01 sec.
dipyrone
(dī´pirōn),
n an analgesic, antiinflammatory, and antipyretic agent that is rarely used because of a high incidence of agranulocytosis.

dipyrone
an analgesic and antipyretic agent, used also as an antispasmodic in equine colic. Overdosing may cause defective blood clotting, leukopenia and agranulocytosis, hemolytic anemia and convulsive episodes.


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The nonsteroidal agent dipyrone (metamizole) was banned by the United States Federal Drug Administration (FDA) in the late 1970s after it was associated with myelotoxicity.
Non-steroidal anti-inflammatory drugs such as carprofen, dipyrone, eltenac, flunixin, ketoprofen, meloxicam, phenylbutazone and vedaprofen were among those at the centre of the study, along with the diuretic furosemide.
Med Res Rev 16: 51-86 Pompeia C, Boaventura MF, Cud R (2001) Antiapoptotic effect of dipyrone on HL-60, Jurkat and Raji cell lines submitted to UV irradiation, arachidonic acid and cycloheximide treatments.
 
 
 
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