diosgenin


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di·os·gen·in

(dī-os'jen-in),
A steroid sapogenin found in the roots of plants such as the yam; its steroid portion serves as a source from which pregnenolone and progesterone can be prepared.
Synonym(s): nitogenin

diosgenin

Herbal medicine
A steroid saponin closely related to human sex hormones, corticosteroids, vitamin D and cardiac glycosides, which is present in wild yam (Dioscorea species) and Beth root (Trillium erectum). Diosgenin is used for the commercial synthesis of cortisone, pregnenolone, progesterone and other steroids.
References in periodicals archive ?
Diosgenin inhibits the migration of human breast cancer MDA-MB-231 cells by suppressing Vav2 activity.
As previously strengthen, the best sclareol MIP system, according to IF parameter, is MIP-AN:AA-80:20, which has intermediate values both for N and K parameters, but which also represents the optimized solution of molecularly imprinting sclareol or diosgenin in an AN:AA matrix [1, 13].
Diosterol(TM) is standardized to contain bioactive fractions rich in steroidal furostanolic saponins and glycosides: Progenin III, Pseudoprotodioscin, Methyl Protodioscin, Dioscin, Protodioscin, Iridoid Glycosides, Diosgenin and 5a-Hydroxy Laxogenin.
Other spice-derived phytochemicals, such as capsaicin, cardamonin, dibenzoylmethane, diosgenin, gambogic acid, gingerol, thyoquinone, urosolic acid and zerumbone have been show the ability to suppress NF-kB activation in a similar manner.
Diosgenin in fenugreek is a steroidal sapogenin and is one of the compounds of fenugreek extract which acts as cortisone, and consequently, reduces anxiety (19).
Wild yam contains the glycoside diosgenin, which has been shown to have an anaboliclike effect or the ability to increase muscle mass (18) Licorice root acts as an adaptogen and also has anti-inflammatory properties.
A phytoestrogen (plant estrogen) called diosgenin found in wild yams can be converted in a laboratory into progesterone.
Tubers rich in diosgenin and yield cortisone, a steroid hormone Dipsacus inermis Wall.
American biochemist Russell Marker discovered the process by which a substance known as diosgenin, an excellent raw material for making synthetic steroids, was extracted from Mexican wild yams known as barbasco.
From increasing male libido, improving digestion, aiding milk production in lactating women and enlarging breasts in non-lactating women, fenugreek has proven to be beneficial and contains protein, vitamin C, niacin, potassium and diosgenin - a compound with properties similar to estrogen.
Sarath says it is possible that diosgenin, which has been linked to digestive problems in livestock, may have compensated for the reduced lignin by helping wreak similar havoc on fall armyworms that attempted to feed on the low-lignin lines during tests.
Wild yam root contains steroidal saponins with diosgenin as the aglycone (Bone 2003a).