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dimethyl sulfoxide

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dimethyl sulfoxide /di·meth·yl sulf·ox·ide/ (DMSO) (di-meth´il sul-fok´sīd) a powerful solvent with the ability to penetrate plant and animal tissues and to preserve living cells during freezing; it is instilled into the bladder for relief of interstitial cystitis and has been proposed as a topical analgesic and antiinflammatory agent and for increasing penetrability of other substances.
dimethyl sulfoxide (DMSO)
[dīmeth′il]
an organic solvent used as an antiinflammatory agent.
indications It is instilled into the bladder for the treatment of interstitial cystitis.
contraindication Known hypersensitivity to this drug prohibits its use.
adverse effects Among the most serious adverse reactions are GI disturbances, photophobia, disturbance of color vision, and headache. A garliclike body odor and taste in the mouth may occur. When applied topically, it can cause local irritations and carry toxins into the systemic circulation.

DMSO 
dimethyl sulfoxide, an industrial solvent that has the ability to penetrate plant and animal tissues and to preserve living cells during freezing. It has been used investigationally as an agent to increase the penetrability of other substances and as a topical analgesic and antiinflammatory. It has been approved by the U.S. Food and Drug Administration in a 50 per cent solution for direct instillation into the bladder for the treatment of interstitial cystitis. A 90 per cent solution, which has been approved only for veterinary use, is believed by some to be beneficial in the treatment of muscle sprains and strains, arthritis, spinal cord injuries, and the aftereffects of stroke when it is applied externally and absorbed by the skin. Claims that it is effective for treating these disorders in humans have not been validated by research studies. It has been shown to produce some short-term side effects.

dimethyl sulfoxide (dī·meˑ·thl sl·fksˑ·īd),
n an industrial solvent used as a treatment for interstitial cystitis; also used as an analgesic and antiinflammatory for muscle aches and arthritic conditions. Caution should be used in selecting high-quality dimethyl sulfoxide because any contaminants and toxins present in it are transported directly into the bloodstream.

dimethyl sulfoxide
(dīmeth´l sulfok´sīd),
n an antiinflammatory agent and organic solvent.
dimethylbenzene (dīmeth´ilben´zēn),
n See xylene.

dimethyl sulfoxide
see dmso.


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The polymer is soluble in dimethyl form amid (DMF), 1-methyl-2-pyrrolidone and dimethyl sulfoxide (DMSO) solvents.
Common surgical treatments include widening of the urethra ("dilation"); bladder distention ("hydrodistention"), in which the bladder is filled with water to a high pressure; and bladder instillation, in which chemicals are put into the bladder (including silver nitrate, oxychlorosene [Chlorpactin WCS-90], and the organic solvent dimethyl sulfoxide [DMSO]).
A broad variety of other drugs and toxins have been reported to cause bradycardia, including lithium, paclitaxel, toluene, dimethyl sulfoxide (DMSO), topical ophthalmic acetylcholine, fentanyl, alfentanil, sufentanil, reserpine, and clonidine.
 
 
 
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