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dimer
(redirected from Dimerizes)

   Also found in: Wikipedia 0.04 sec.
dimer /di·mer/ (di´mer)
1. a compound formed by combination of two identical molecules.
2. a capsomer having two structural subunits.

di·mer (dmr)
n.
1. A molecule consisting of two identical simpler molecules.
2. A chemical compound consisting of such molecules.

di·meric (d-mrk) adj.

dimer
chemical compound formed by the union of two identical molecules.

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In hypoxia or after metal exposure, the [alpha] subunit dimerizes with a [beta] subunit and translocates to the nucleus.
After ligand binding within the PAS domain, the cytosolic Ahr undergoes a conformational change, dissociates from two 90-kDa heat shock proteins and the hepatitis B virus X-associated protein 2, and translocates to the nucleus where it dimerizes with Arnt (Carver and Bradfield 1997).
Upon binding of estrogen to the estrogen receptor (ER), the ligand-receptor complex dimerizes and mediates the transcriptional activity of genes containing estrogen response elements (EREs) and/or AP-1 sites.
 
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