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dimer |
Also found in: Wikipedia | 0.04 sec. |
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dimer /di·mer/ (di´mer) 1. a compound formed by combination of two identical molecules. 2. a capsomer having two structural subunits.
dimer chemical compound formed by the union of two identical molecules. |
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? Mentioned in | ? References in periodicals archive | |
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In hypoxia or after metal exposure, the [alpha] subunit dimerizes with a [beta] subunit and translocates to the nucleus. After ligand binding within the PAS domain, the cytosolic Ahr undergoes a conformational change, dissociates from two 90-kDa heat shock proteins and the hepatitis B virus X-associated protein 2, and translocates to the nucleus where it dimerizes with Arnt (Carver and Bradfield 1997). Upon binding of estrogen to the estrogen receptor (ER), the ligand-receptor complex dimerizes and mediates the transcriptional activity of genes containing estrogen response elements (EREs) and/or AP-1 sites. |
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