dilated cardiomyopathy

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Related to dilated cardiomyopathy: hypertrophic cardiomyopathy

di·lat·ed car·di·o·my·op·a·thy

decreased function of the left ventricle associated with its dilation; most patients have global hypokinesia, although discrete regional wall movement abnormalities may occur; usually manifested by signs of overall cardiac failure, with congestive findings, as well as by fatigue indicative of a low output state.

dilated cardiomyopathy

Cardiology The most common cardiomyopathy in the US, which is usually idiopathic and characterized by ↑ ventricular size and impaired ventricular function Etiology Infection–eg coxsackievirus, CMV, HIV, diphtheria, trichinosis, inflammation–eg connective tissue disease, sarcoidosis, metabolic–eg hypothyroidism, thyrotoxicosis, DM, Cushing's disease, thiamine, selenium deficiency, or toxic–eg cocaine, antiretroviral agents, lead, cobalt, ethanol, phenothiazines insults; ±20% of DCs, there is a familial component Prognosis Often progresses to CHF accompanied by mitral and tricuspid valve insufficiency Complications Conduction defects–eg atrial & ventricular tachyarrhythmias and fibrillation Management Supportive–eg rest, weight control, smoking cessation, ↓ physical activity during exacerbation; therapies that may be effective include ACE inhibitors, anticoagulation, digoxin, diuretics, implantable defibillators, nitrates, potassium, magnesium repletion Investigational modalities Amiodarone, amlodipine, beta-blockers, dual-chamber pacing, felodipine, pimobendan, vesnarinone; recombinant hGH has been reported to ↑ myocardial mass and ↓ left ventricular chamber size, resulting in improved hemodynamics, myocardial energy metabolism, clinical status

Beck·er dis·ease

(bek'ĕr di-zēz')
An obscure South African cardiomyopathy leading to rapidly fatal congestive heart failure and idiopathic mural endomyocardial disease.
Synonym(s): dilated cardiomyopathy.

Dilated cardiomyopathy

Also called congestive cardiomyopathy; cardiomyopathy in which the walls of the heart chambers stretch, enlarging the heart ventricles so they can hold a greater volume of blood than normal.


a state of dilatation.

dilated cardiomyopathy
see congestive cardiomyopathy.
dilated pupil syndrome
see feline dysautonomia (Key-Gaskell syndrome).
References in periodicals archive ?
Third, an in-depth genetic analysis conducted in one of the dilated cardiomyopathy families with a member who had peripartum cardiomyopathy revealed a mutation in TNNC1, the gene encoding cardiac troponin C.
The course of idiopathic dilated cardiomyopathy in New Zealand.
Dilated cardiomyopathy in an adult human immunodeficiency virus type 1-positivepatient treated with a zidovudine-containing antiretroviral regimen.
Causes of heart failure were idiopathic dilated cardiomyopathy (IDC) in 12 patients (8 men and 4 women, ages 31 to 66 years), and ischemic heart disease (ischemic dilated cardiomyopathy, ISCDC) in 11 patients (8 men and 3 women, ages 32 to 65 years).
A review of the Dilated Cardiomyopathy products under development by companies and universities/research institutes based on information derived from company and industry-specific sources.
Epidemiology of idiopathic dilated cardiomyopathy and hypertrophic cardiomyopathy: a population-based study in Olmsted Country, Minnesota, 1975-1984.
The DEFINITE trial, which was published in 2004, randomized 458 patients with nonischemic dilated cardiomyopathy (DCM) and a left ventricular ejection fraction of less than 36% to receive standard medical therapy alone or medical therapy plus an ICD (N.
After undergoing heart checks, a heart specialist told him he had dilated cardiomyopathy.
Consultant pathologist Dr Adrian Warfield said Mr Newbury's heart had become massively enlarged and had been struggling to circulate blood because of a condition called dilated cardiomyopathy.
The case of a 41-year-old male who presented with severe symptomatic congestive heart failure, and was subsequently diagnosed with dilated cardiomyopathy secondary to hyperthyroidism, is presented.
Other researchers have identified an accumulation in the hearts of those with idiopathic dilated cardiomyopathy thousands of times higher than even the surrounding tissues of the same individual (Frustaci et al.