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Dilated cardiomyopathy
(redirected from Dilated cardial myopathy)

   Also found in: Wikipedia 0.01 sec.
Dilated cardiomyopathy
Also called congestive cardiomyopathy; cardiomyopathy in which the walls of the heart chambers stretch, enlarging the heart ventricles so they can hold a greater volume of blood than normal.

dilated
a state of dilatation.

dilated cardiomyopathy
see congestive cardiomyopathy.
dilated pupil syndrome
see feline dysautonomia (Key-Gaskell syndrome).

dilated cardiomyopathy
Cardiology The most common cardiomyopathy in the US, which is usually idiopathic and characterized by ↑ ventricular size and impaired ventricular function Etiology Infection–eg coxsackievirus, CMV, HIV, diphtheria, trichinosis, inflammation–eg connective tissue disease, sarcoidosis, metabolic–eg hypothyroidism, thyrotoxicosis, DM, Cushing's disease, thiamine, selenium deficiency, or toxic–eg cocaine, antiretroviral agents, lead, cobalt, ethanol, phenothiazines insults; ±20% of DCs, there is a familial component Prognosis Often progresses to CHF accompanied by mitral and tricuspid valve insufficiency Complications Conduction defects–eg atrial & ventricular tachyarrhythmias and fibrillation Management Supportive–eg rest, weight control, smoking cessation, ↓ physical activity during exacerbation; therapies that may be effective include ACE inhibitors, anticoagulation, digoxin, diuretics, implantable defibillators, nitrates, potassium, magnesium repletion Investigational modalities Amiodarone, amlodipine, beta-blockers, dual-chamber pacing, felodipine, pimobendan, vesnarinone; recombinant hGH has been reported to ↑ myocardial mass and ↓ left ventricular chamber size, resulting in improved hemodynamics, myocardial energy metabolism, clinical status


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