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diisopropyl phosphorofluoridate
(redirected from Diisopropylfluorophosphate)

   Also found in: Encyclopedia, Wikipedia 0.01 sec.
di-isopropyl phosphorofluoridate, diisopropyl phosphorofluoridate
an ophthalmic cholinergic used as a miotic; called also isoflurophate.


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This is likely to play an important role in neuroprotection against organophosphates: forskolin, which stimulates adenylyl cyclase directly, preserves neural cells from the adverse effects of diisopropylfluorophosphate, potentially by promotion of differentiation, which up-regulates acetylcholinesterase itself (Curtin et al.
Agence de Cooperation Culturelle et Techniques, Paris Aron Y, Kone PP, Simaga A (1986) Les serpents en Cote d'Ivoire: Etude biologique in Resume des communications des premieres journees scientifiques, FAST--Abidjan, p 63 Barstad JAB (1956) The effect of d-turbocurarine on the neuro-muscular blocks caused by diisopropylfluorophosphate and acetylcholine.
Ahlbom and colleagues exposed neonatal mice to a single oral dose of the organophosphate diisopropylfluorophosphate on either postnatal day 3, 10, or 19.
 
 
 
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