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Calcium channel blocker
(redirected from Dihydropyridine CCB)

    Also found in: Wikipedia 0.06 sec.
calcium channel blocker
n.
Any of a class of drugs that inhibit movement of calcium ions across a cell membrane, used in the treatment of cardiovascular disorders.
Calcium channel blocker
A drug that relaxes blood vessels and lowers blood pressure.
Mentioned in: Heart Failure, Hypertrophic Cardiomyopathy
calcium channel blocker
a drug, such as nifedipine or verapamil, that selectively blocks the influx of calcium ions through a specific ion channel (the slow channel or calcium channel) of cardiac muscle and smooth muscle cells; used in the treatment of cardiac arrhythmias. Calcium channel blockers act to control arrhythmias by slowing the rate of sinoatrial (SA) node discharge and the conduction velocity through the atrioventricular (AV) node. Called also calcium blocker, calcium antagonist.
calcium channel blocker Calcium channel antagonist Pharmacology An agent that blocks entry of Ca2+ into cells, thereby preventing cell dealth and loss of function due to excess Ca2+; CCBs are used to manage heart conditions and stroke, may be useful for Alzheimer's disease


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4, 43) The utility of adding a dihydropyridine CCB (eg, amlodipine) to the regimen of a patient with diabetic nephropathy has previously been questioned; however, the NKF guidelines state that dihydropyridine CCBs can be used safely in combination with an ACE inhibitor or an ARB.
Improving antihypertensive therapy in patients with diabetic ... by Mende, Christian W. / Southern Medical Journal
Lotrel offers a new alternative to increasing dosages, switching to different classes, or progressing to two-drug therapy when patients do not adequately respond to dihydropyridine CCBs or ACE inhibitors," said Dr.
CIBA INTRODUCES NEW HYPERTENSION THERAPY; First in New Category by Business Wire
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