| Dictionary, Encyclopedia and Thesaurus - The Free Dictionary 1,506,326,487 visitors served. |
|
Dictionary/ thesaurus | Medical dictionary | Legal dictionary | Financial dictionary | Acronyms | Idioms | Encyclopedia | Wikipedia encyclopedia | ? |
Didronel |
Also found in: Wikipedia | 0.04 sec. |
Didronel, trademark for a calcium regulator (etidronate disodium). etidronate disodium Didronel Pharmacologic class: Bisphosphonate Therapeutic class: Bone resorption inhibitor, hypocalcemic agent Pregnancy risk category B (oral use), C (I.V. use) ActionBlocks calcium absorption, slowing bone metabolism and reducing bone resorption and formation AvailabilityInjection: 300 mg/ampule in 6-ml ampules Tablets: 200 mg, 400 mg ⊘Indications and dosages ➣ Paget's disease Adults: 5 to 10 mg/kg P.O. daily as a single dose for up to 6 months, or 11 to 20 mg/kg P.O. daily for up to 3 months ➣ Heterotopic ossification after hip replacement Adults: 20 mg/kg P.O. daily for 1 month before and 3 months after surgery ➣ Heterotopic ossification in spinal cord injury Adults: Initially, 20 mg/kg P.O. daily for 2 weeks, decreased to 10 mg/kg P.O. daily for 10 weeks ➣ Hypercalcemia related to cancer Adults: 7.5 mg/kg/day I.V. infused over at least 2 hours for 3 consecutive days; may continue infusion for up to 7 days if necessary. P.O. dosing may begin after last infusion. Contraindications• Hypersensitivity to drug or its components PrecautionsUse cautiously in: Administration• For I.V. use, dilute with 250 ml of normal saline solution. Infuse slowly over at least 2 hours.
Adverse reactionsAll reactions occur only with I.V. use unless otherwise noted. CNS: seizures GI: nausea, constipation, stomatitis Hematologic: anemia Metabolic: hypomagnesemia, hypophosphatemia, fluid overload Musculoskeletal: bone pain and tenderness, fractures (all with oral use) Respiratory: dyspnea Skin: rash (with oral use) Other: taste loss, metallic taste, fever InteractionsDrug-drug. Antacids; buffers containing aluminum, calcium, iron, or magnesium; mineral supplements: decreased etidronate absorption Calcitonin: additive hypocalcemic effect Warfarin: increased prothrombin time Drug-diagnostic tests. Blood urea nitrogen (BUN), creatinine: increased levels Calcium, magnesium: decreased levels Liver function tests: elevated values Drug-food. Foods high in aluminum, calcium, iron, or magnesium: decreased etidronate absorption Patient monitoring• Monitor fluid intake and output. Patient teaching• Instruct patient not to take drug with food because of decreased drug absorption. Didronel® Etidronate, see there How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
|
| ? Mentioned in | ? References in periodicals archive | |
|---|---|---|
P&G's current pharmaceutical brands include Actonel, Didronel, Asacol and Macrobid. P&G's current pharmaceutical brands include Actonel, Didronel, Asacol and Macrobid. This includes Tide, Ariel, Crest, Pantene Pro-V, Always, Whisper, Pringles, Pampers, Oil of Olay, Vicks and Didronel. |
| Medical Dictionary |
| Free Tools: |
For surfers:
Browser extension |
Word of the Day |
Help
For webmasters: Free content | Linking | Lookup box | Double-click lookup | Partner with us |
|---|