dichloroacetic acid

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dichloroacetic acid

50:50 mix of trichloro- and monochloroacetic acids in saturated solution
References in periodicals archive ?
At the ASCI meeting, Arieff described what happened when acidotic dogs were given dichloroacetate, which stimulates an enzyme involved in maintaining the proper acid-base balance.
Contribution of dichloroacetate and trichloroacetate to liver tumor induction in mice by trichloroethylene.
Dichloroacetate, which increases flux into the Krebs cycle, as well as in termediates of the Krebs cycle, such as acetate and citrate, also enhanced the levels of PPSS I mRNA.
2000) Effects of pdh activation by dichloroacetate in human skeletal muscle during exercise in hypoxia.
Therapeutic potential of dichloroacetate for pyruvate dehydrogenase complex deficiency.
com is the only source for Vet-DCA(TM), the purest pharmaceutical- grade dichloroacetate (DCA) available today.
Reviews of case studies reveal that IV and oral preparations of dichloroacetate used during acute stroke and prophylaxis of stroke have a decreased number and severity of strokes in patients with MELAS syndrome.
The purpose of this clinical trial is to determine whether the drug NTBC(Nitisione, Orfadinin TM) reduces or prevents the undesirable side effects (toxicity), of the investigational drug, dichloroacetate (DCA), in patients with Congenital Lactic Acidosis.
Such is the case with dichloroacetate, or DCA, a simple molecule which has been touted as a potential treatment for certain cancers.
Dichloroacetate, a metabolic modulator, prevents and reverses chronic hypoxic pulmonary hypertension in rats: role of increased expression and activity of voltage gated potassium channels.
The new compound called, mitaplatin, combines cisplatin with another compound, dichloroacetate (DCA), that alters the properties of mitochondria selectively in cancer cells.
Reduction of serum lactate by sodium dichloroacetate, and human pharmacokinetic-pharmacodynamic relationships.

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