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dexrazoxane

   Also found in: Wikipedia 0.01 sec.
dexrazoxane /dex·ra·zox·ane/ (-ra-zok´sān) a cardioprotectant used in chemotherapy to counteract doxorubicin-induced cardiomyopathy.
dexrazoxane,
a cardioprotective agent.
indications It is prescribed in the protection of women from heart problems caused by doxorubicin treatment of breast cancer.
contraindications It should not be given to patients with an allergy to dexrazoxane or any of its components or who are receiving chemotherapy that does not contain an anthracycline drug.
adverse effects The side effects most often reported include pain on or at the injection site, flushing, bruising, rash, numbness, or general body discomfort.

dexrazoxane [deks″ra-zok´sān]
a derivative of ethylenediaminetetraacetic acid (EDTA) used as a cardioprotectant in antineoplastic therapy to counteract cardiomyopathy induced by doxorubicin; administered intravenously.


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Chemotherapy protective agents Amifostine, Mesna, Dexrazoxane Chemoprotective agents are drugs that are used with chemotherapy to minimise the side effects.
Other potentially useful antidotes include dimethyl sulfoxide, dexrazoxane, and growth factors.
 
 
 
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