Developmental Toxicity


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Related to Developmental Toxicity: reproductive toxicity

toxicity

 [tok-sis´ĭ-te]
the quality of being poisonous, especially the degree of virulence of a toxic microbe or of a poison.
developmental toxicity the extent to which a toxin produces adverse effects on a developing embryo or fetus; see also teratogenesis.
maternal toxicity a toxic effect on a pregnant woman or nursing mother, as opposed to one affecting an embryo, fetus, or nursing infant.
The occurrence of adverse effects on a developing organism attributed to exposure to a chemical before conception, in utero, after birth, or during sexual maturation
References in periodicals archive ?
Developmental toxicity is shown by the disubstituted methyl-, butyl-, and octyltins, but not by the corresponding monosubstituted compounds.
The drug caused minor developmental toxicity in rat fetuses that was reversed after birth, and shortening of the gestation period.
In addition to elevated cancer risk and disruption of the endocrine system, growing evidence supports developmental toxicity from prenatal or early postnatal exposure to PAHs (Perera et al.
The 27 chapters by a group of North American pharmacists, physicians, and nurses specializing in maternal-fetal medicine provide information often lacking in pharmacy training, including discussion of physiologic changes, developmental toxicity, drug use and lactation, use of over-the-counter medications, teratology risk assessment and counseling, drug therapy for complications unique to pregnancy, and treatment of common chronic diseases such as depression, epilepsy, infectious disease, nausea and vomiting, and autoimmune diseases in pregnancy.
The current study was performed to confirm the developmental toxicity of the ionic liquid 1-decyl-3-methylimidazolium chloride ([C10mim]Cl).
Doctoral level subject matter experts (SMEs) in endocrine disruption, ecotoxicity, developmental toxicity, genotoxicity, immunotoxicity, and quantitative structure activity relationships make up the 2 branches of the Portfolio (Toxicity Evaluation Program; Health Effects Research Program).
This study confirms that, as we have suspected, exposure to (perfluorooctane sulfonate and perfluorooctanoate) is fairly universal; this is of particular concern because of the potential toxicity, especially developmental toxicity, for these chemicals and the lack of information about health risks at these exposure levels," said APHA member Lynn Goldman, MD, MPH, co-author of the study.
NTP-CERHR Expert Panel Report on the Reproductive and Developmental Toxicity of Soy Formula.
Numerous studies have shown Se supplementation counteracts the negative impacts of exposure to Hg, particularly in regard to neurotoxicity, fetotoxicity, and developmental toxicity.
Aripiprazole is in pregnancy category C, indicating that developmental toxicity was noted in animal studies.
Abacavir is associated with developmental toxicity in rats including decreased fetal body weight and skeletal malformations.
Though his panel slogged through nearly 600 studies on DEHP and almost as many for another six phthalates, it didn't find answers to many pressing questions about developmental toxicity.

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