5) These symptoms depend on the sites of impaired desmosome
function and usually vary in their presentation, such as oral pain, stinging, sore throat, hoarseness, dysphonia, dysphagia, odynophagia, epistaxis, nasal congestion, blood-tinged mucus, otalgia, ear canal obstruction, vaginal discharge and pain, ocular pain, and excessive tearing.
27) Unlike FDCS, interdigitating dendritic cell sarcomas are diffusely positive for S100, negative for dendritic cell markers (CD21, CD35), and lack desmosomes
on electron microscopy.
One of the studies also showed that the adipogenic stimulation intensified changes in the desmosomes
structure and lipid accumulation.
Electron microscopy shows the characteristics of mesothelial cells-slender microvilli on the luminal surface of the cells, desmosomes
, intracytoplasmic intermediate filaments, endoplasmic reticulum, and dilated mitochondria.
Both ETA and ETB target and destroy desmoglein-1, a molecule found in desmosomes
that plays an important role in cell-cell adhesion in the stratum granulosum of the epidermis2.
Mutations in this gene cause the disease by altering the formation or stability of desmosomes
Many of the fibers appear to terminate at desmosomes
in the glial membranes (fig.
TEHRAN (FNA)- Scientists at the University of Manchester have made an important discovery about how cells in the skin and heart are bound together through structures called desmosomes
were observed, serving as pathways connecting neighboring Tps.
SSSS, also known as Pemphigus neonatorum or Ritter's disease, is caused by exotoxins released by Staphylococcus aureus, which act as proteases breaking down desmosomes
v) the findings of the ultrastructural studies of their patients' bladder lesions showed an absence of urothelial-cell differentiation such as asymmetric membranes or numerous desmosomes
in the nephrogenic adenoma cells;
They include discussion of psoriasis, cutaneous oncology, embryonic stem cell therapies, genetics, epidermal barriers, desmosomes
, sweat gland progenitors, adipocytes, melanocytes, wound healing and skin regeneration, immunology, the macroenvironmental regulation of hair cycling and collective regenerative behavior, the microbial ecology of the skin, aging of the skin, long noncoding RNA, epigenetic regulation of epidermal differentiation, cutaneous notch signaling, alopecia, gene therapy, and cell therapy.