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desmosomes |
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desmosomes, n.pl See epithelium, desmosomes of. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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These genes encode components of desmosomes (DSG2), gap junctions (CX26), tight junctions (CLDN4, CLDN7), the cornified envelope (SPRRIA, 2A, 2B, 2E, 2F, 2G, 2I, 2J), intermediate filaments (KRT19), and a variety of cell-surface and extracellular-matrix glycoproteins (SPP1, BGP1, BGP2, MUC1, TROP2, CLU). The finding of epithelial elements, mature desmosomes, and tonofilaments in the original neoplasm secured the diagnosis of spindle-cell squamous carcinoma. Desmosomes are adhesive structures that are intimately involved in maintaining the structure, function and integrity of the skin and other epithelial tissues. |
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