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desaturase

   Also found in: Wikipedia 0.01 sec.
desaturase
an enzyme capable of catalyzing desaturation of fatty acids.


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When the chain reaches 18 atoms, an enzyme called desaturase puts in the double bond to form oleic acid (SN: 5/31/97, p.
Specific examples of current projects include acyl-coenzyme A diacylglycerol acyltransferase (DGAT), 11 beta-hydroxysteroid dehydrogenase (11 beta-HSD), desaturases, and a family of histone deacetylases (HDACs).
1999) found that coplanar PCBs have a significant effect on the reduced synthesis of physiologically essential long-chain unsaturated fatty acids, such as arachidonic acid in rat liver, by suppressing delta-5 and delta-6 desaturase activities and thus allowing the omega-6 parent fatty acid, linoleic acid, to accumulate.
 
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