dermatan sulfate

(redirected from Dermatan sulphate)

der·ma·tan sul·fate

an anticoagulant with properties similar to those of heparin and sharing with heparin a sulfated mucopolysaccharide structure; a repeating polymer of l-iduronic acid and N-acetyl-d-galactosamine. O-Sulfation of iduronic acid residues at the C-2 position and of galactosamine residues at the C-4 and C-6 positions occurs to a variable extent.

dermatan sulfate

(dûr′mə-tăn′)
n.
A glycosaminoglycan that is a structural component of certain body tissues, especially the skin.

der·ma·tan sul·fate

(dĕrmă-tan sŭlfāt)
Anticoagulant with properties similar to those of heparin.

dermatan sulfate

a component of the acellular ground substance of skin.
References in periodicals archive ?
GAG family include unsulphated hyaluronic acid (HA), sulphated dermatan sulphate (DS), keratin sulphate (KS), heparin sulphate (HS) and chondroitin sulphates (C4S, C6S).
Hurler's syndrome (MPS IH), which is a prototype of MPS is caused by a deficiency of alpha-L-iduronidase due to a loss of function mutation leading to excessive accumulation of partially degraded GAGs, dermatan sulphate and heparan sulphate within the cells.
The major classes of GAG include hyaluronic acid (HA), heparin sulphate, heparin, chondroitin 4-sulphate, chondroitin 6-sulphate, dermatan sulphate and keratan sulphate.
Heparin and dermatan sulphate induced capacitation of frozen-thawed bull spermatozoa measured by merocyanine-540.
3) The metabolism of heparan and dermatan sulphate is normal in Morquio syndrome, which is why patients with Morquio syndrome do not have mental retardation.
Heparan, keratan and dermatan sulphate can be distinguished by electrophoresis techniques to differentiate between the mucopolysaccharidoses.
Two of the sugars that are commonly accumulated in MPS diseases are heparan sulphate (HS) and dermatan sulphate (DS).
For example, dermatan sulphate, which is extracted from cow hides, is reported to have anti-inflammatory properties and inhibit the formation of blood clots.
Determination of human urinary hyaluronic acid, chondroitin sulphate and dermatan sulphate as their unsaturated disaccharides by high-performance liquid chromatography.