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derivative chromosome |
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derivative chromosome, a chromosomal aberration caused by translocation. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Significant advantages of our assay format include: 1) both derivative chromosomes are detected by separate fusion signals, 2) overall assay sensitivity is increased due to the complete absence of false positive cells, 3) assay accuracy is increased because probes are derived from regions outside of all known breakpoints, and 4) there is no reduction in actual signal intensity, since probes do not overlap any of the breakpoints. Compared to conventional probes that identify only one derivative chromosome with a single fusion signal, our dual color, dual fusion probes detect very small numbers of tumor cells present in a population of normal cells, and do not generate false positive signals", Dr. |
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