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selegiline
(redirected from Deprenyl)

    Also found in: Wikipedia 0.06 sec.
selegiline /se·le·gil·ine/ (se-lej´i-len) an antiparkinsonian agent used as the hydrochloride salt in conjunction with levodopa and carbidopa.
selegiline (seˑ·l·gi·lēnˈ),
n an MAO-B inhibitor used to treat Parkinson's disease. It also acts as an antioxidant and an immunostimulant, protects nerve tissue from degeneration, and has positive effects on cognition. Also called
deprenyl or
l-deprenyl.
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Although 100 mg/kg gentamicin (sc) led to nephrotoxicity at 24 hr, no hepatotoxicity was associated with it, nor was hepatotoxicity detected with deprenyl or lazabemide.
Discriminating different classes of toxicants by transcript profiling by Ruepp, Stefan / Environmental Health Perspectives
Bova also reviews other scientific test results that show promise in extending life--such as hormone replacement therapy; the nutritional supplement DHEA and low-calorie diets; and the drug deprenyl, currently used to control symptoms of Parkinson's disease.
Immortality by Silva, David / The Humanist
Ruehl is vice president of scientific affairs for Deprenyl Animal Health in Overland Park, Kan.
Dogs and cats in their dotage by Milius, Susan / Science News
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