deoxyribonuclease

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deoxyribonuclease

 (DNase) [de-ok″sĭ-ri″bo-nu´kle-ās]
an enzyme that catalyzes the hydrolysis (depolymerization) of deoxyribonucleic acid (DNA).

de·ox·y·ri·bo·nu·cle·ase (DNAse, DNAase, DNase),

(de-oks'ē-rī'bō-nū'klē-ās),
Any enzyme (phosphodiesterase) hydrolyzing phosphodiester bonds in DNA.
See also: endonuclease, nuclease.

deoxyribonuclease

/de·oxy·ri·bo·nu·cle·ase/ (DNase) (-ri″bo-noo´kle-ās) any nuclease catalyzing the cleavage of phosphate ester linkages in deoxyribonucleic acids (DNA); separated by whether they cleave internal bonds or bonds at termini.

deoxyribonuclease

(dē-ŏk′sē-rī′bō-no͞o′klē-ās′, -āz′, -nyo͞o′-)
n.
DNase.

APEX1

A gene on chromosome 14q11.2 that encodes a major apurinic/apyrimidinic (AP) endoDNAase, which is involved in the DNA base excision repair (BER) pathway of DNA lesions induced by oxidative and alkylating agents, and in the redox regulation of transcriptional factors.

de·ox·y·ri·bo·nu·cle·ase

(DNase) (de-oks'ē-rī'bō-nū'klē-ās)
Any enzyme (phosphodiesterase) hydrolyzing phosphodiester bonds in DNA.
See also: endonuclease, nuclease

deoxyribonuclease

An enzyme that cuts DNA strands by breaking PHOSPHODIESTER BONDS.

deoxyribonuclease (DNAse)

see NUCLEASE.

deoxyribonuclease

an enzyme that catalyzes the hydrolysis (depolymerization) of deoxyribonucleic acid (DNA). Abbreviated DNase.
References in periodicals archive ?
Lazarus RA, Wagener JS (2007) Recombinant Human Deoxyribonuclease I".
Taper HS (2008) Altered deoxyribonuclease activity in cancer cells and its role in nontoxic adjuvant cancer therapy with mixed vitamins C and K3.
Baranovski AG, Byneva BN, Nevincki GA (2004) Human deoxyribonuclease.
Androgen Ablation Leads to an Upregulation and Intranuclear Accumulation of Deoxyribonuclease I in Rat Prostate Epithelial Cells Paralleling Their Apoptotic Elimination J.
An abrupt elevation of the serum deoxyribonuclease I (DNase I) activity in acute myocardial infarction [Abstract].
Human genetically polymorphic deoxyribonuclease: purification, characterization, and multiplicity of urine deoxyribonuclease I.
Human urine deoxyribonuclease II (DNase II) isozymes: a novel immuncaffinity purification, biochemical multiplicity, genetic heterogeneity, and broad distribution among tissues and body fluids.

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