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Nucleotide |
Also found in: Encyclopedia, Wikipedia, Hutchinson | 0.06 sec. |
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nucleotide /nu·cleo·tide/ (noo´kle-o-tid?) one of the compounds into which nucleic acid is split by action of nuclease; nucleotides are composed of a base (purine or pyrimidine), a sugar (ribose or deoxyribose), and a phosphate group. cyclic nucleotides those in which the phosphate group bonds to two atoms of the sugar forming a ring, as in cyclic AMP and cyclic GMP, which act as intracellular second messengers.
Nucleotide Any of a group of organic molecules that link together to form the building blocks of DNA or RNA. Mentioned in: Myotonic Dystrophy nucleotide any of a group of compounds obtained by hydrolysis of nucleic acids, consisting of a purine or pyrimidine base linked to a sugar (ribose or deoxyribose), which in turn is esterified with phosphoric acid. See also nucleoside, deoxyribonucleic acid. cyclic n's those in which the phosphate group bonds to two atoms of the sugar forming a ring, as in cyclic AMP and cyclic GMP, which act as intracellular second messengers. nucleotide sequences see dna sequencing. single nucleotide polymorphisms (SNPs) single base pair changes that distinguish one individual from another of the same species. |
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? Mentioned in | ? References in periodicals archive | |
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c) A, C, G, and T refer to the four deoxynucleotides that DNA comprises. In the first step to assay for recombination, DNA (125,250, 500, and 1,000 ng) was suspended in a 50- [micro] l solution containing 200 [micro] M deoxynucleotides, 50 mM KCl, 10 mM Tris, pH 8. The BioArray(TM) CGH Labeling System is optimized for the preparation of Cy3 and Cy5 labeled DNA and provides all necessary reagents for random primed labeling, including primers, Klenow DNA polymerase, and Enzo's proprietary Cy3 and Cy5 labeled deoxynucleotides. |
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