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dense deposit disease |
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dense deposit disease Type II membranoproliferative glomerulonephritis Nephrology A glomerulopathy in which electron-dense material–usually complement C3 is deposited in the glomerular capillary basement membrane, with ↓ serum C3,
due to alternate complement pathway activation, in the face of normal C4; there is patchy mesangial proliferation in Bowman's capsule, and accumulation of basement membrane material in the peritubular capillaries and arterioles Prognosis Poor.
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