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dendritic spine |
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The size of the dendritic arbor and the density of dendritic spines determine the total synaptic input a neuron can receive (Engert and Bonhoeffer 1999; Purves 1988) and influence the types and distribution of these inputs (Miller and Jacobs 1984; Schuman 1997; Sejnowski 1997). When they examined the animals' brains, they found that hippocampal cells in those mice that had received ghrelin had about a quarter more dendritic spines, which are specialized nerve cell connections associated with learning. Even in their 1-month-old mice, more than 70 percent of dendritic spines persisted for more than a month. |
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